Protein Alignment Cyp18a1 and cyp-33D3

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_507679.2
• Gene: cyp-33D3 / 189444
• WormBaseID: WBGene00012448
• Length: 495
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 167/515 - (32%)
• Similarity: 275/515 - (53%)
• Gaps: 45/515 - (8%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK--HTRFMELAKQYGSLF 88
            ||::|..:     .|.:....:.:.|.|||||..||.:|.||.:.:.|  :..|....|:||.:|
 Worm     3 LLLIFSSI-----FLYFFYHFHWKRRNLPPGPRPLPFLGNLLSLKTLKPGYEAFSNWKKEYGPIF 62

  Fly    89 STRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTL---------NGYGIINSTGKLWKDQR 144
            :..:.::..|:::.|:.::|.|.::     .||...:.|         ..||::::.|.:||:.|
 Worm    63 TFWMANKPFVIIASYEKMKETFVKD-----GDTYVDKQLTHTEKERLGENYGVLDTNGHMWKEHR 122

  Fly   145 RFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMS 209
            ||...:||..|:     ||..||::|:.||.|....|.|..|:.:|:..:|..:|.|||...:.:
 Worm   123 RFTLTQLRDLGL-----GKDLMQEKILMEVEELFKELDAHGGEEIDLPKLIDRSVGNVINLTLFN 182

  Fly   210 TRFSIDD-PKFRRFNFLIEEGMR----LFGEI--HTVDYIPTMQCFPSISTAKNKIAQNRAEMQR 267
            .||.:|. .:|.....|| :|||    .|..:  :.|.:..|:...|::|   .|:...|.|:..
 Worm   183 KRFDMDKRDEFAHLKSLI-DGMRNVTSQFRYLIQYLVPWTSTVLPGPTLS---EKVRAKREELDD 243

  Fly   268 FYQDVIDDHKRSFDPNNIR--DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGM 330
            |:...||:|:...|.:|..  |.|:.||.|.:|.:.:| |.:.|..|    ||..::.||:.||:
 Worm   244 FFYSQIDEHRNEIDFDNTENLDFVEAYLKEQKKREEDG-DFKTFCNK----QLCAMLFDLWIAGL 303

  Fly   331 ETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPL 395
            .|...|:.|...:.|.||:..|::::|||:|:|..||.:..|...||..::.:.|:.|.::|:||
 Worm   304 MTTTMTMTWGLSYYLYNPEVQRKIREELDKVIGNDRLISTADKNDLPYLQAFVTETQRTANIIPL 368

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFG 460
            ...|..|||..::|:.|..|:.||..|::|..|..::.:|.:|:|.|||: .||.:|.:..|||.
 Worm   369 NLIHMTTRDTVIDGFPIQKGTGVIAQISTVMYDEKVFPEPYKFKPERFIE-NGKFKKVDEVIPFS 432

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            :|:|.|||:.|||:|||||||:..:.:|:.......||.|..:....:.|..||..||||
 Worm   433 IGKRQCLGEGLARIELFLFFANIFNRYDVMPDFSGSLPDLDKSKDNFVIPRKFKAVLKRR 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	157/482 (33%)
cyp-33D3	NP_507679.2	p450	26..484	CDD:278495	155/477 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I1197
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I1894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm14091
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.770