Protein Alignment Cyp18a1 and cyp-14A2

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_510204.1
• Gene: cyp-14A2 / 187184
• WormBaseID: WBGene00010706
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 158/525 - (30%)
• Similarity: 266/525 - (50%)
• Gaps: 58/525 - (11%)

  Fly    28 MVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFM-ELAKQYGSLFSTR 91
            |..|.:..||::..::...|.::.|.|.||:.||.||.:|.:.||....:: :|:|.||..|:
 Worm     1 MSILIVAFLVSITVYIAYFYWKVSKYPKGPFPLPFIGNILQIPSENIQEYLDDLSKTYGPCFT-- 63

  Fly    92 LGSQL-TVVMSDYKMIRECF--RREEFTGRPDTP---FMQTLNGYGIINSTGKLWKDQRRFLHDK 150
            |.:.| .:|::||:.::|.|  :.:.|..|.|.|   .:|.....|::.|.|..|:.|||.....
 Worm    64 LWTPLPAIVLTDYEHVKEAFVTQGDAFIYRADRPPETLLQPHLNTGVLFSNGDNWRFQRRTALKI 128

  Fly   151 LRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL-HASDGQPVDMSPVISVAVSNVICSLMMSTRFSI 214
            ||.||:     |:..|::::|..|||.:..| ..:|.:.|||...|.:.|.|||...:.|..:..
 Worm   129 LRDFGL-----GRNLMEEQVMRSVHEMLAQLERIADKKNVDMFWPIQLCVGNVINESLFSYHYKY 188

  Fly   215 DD-PKFRRFNFLIEEGMR-LFGE-IHTVDYIPTMQCFPSI-STAKNKIAQNRAEMQRFYQDVIDD 275
            :| .||..|..::::.:: :.|: |..:...|.::.||.| ....::|.:|....|.|..|.:..
 Worm   189 EDSKKFETFVKVLDKHLKTVQGKTIFLMSAFPWLKHFPVIGELGYHRIKKNIQSYQEFINDEVTS 253

  Fly   276 HKRSFD----PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTT 336
            ..:.:|    |.|   .|..|:.:::::.....|.         ..|...:||.:.|||||...:
 Worm   254 QIKHYDGESEPEN---FVHAYMQQMKQSGNPNLDM---------NNLCASVIDFWLAGMETTSNS 306

  Fly   337 LLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSP 401
            |.|...||::.|:...:|:.|:...||..|||::.|...:|.|::.|.|..|.|:::|:..||:.
 Worm   307 LRWHLAFMMKYPEIQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPILGTHTN 371

  Fly   402 TRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGK-VRKP--EYFIPFGVGR 463
            ..|:.|.|..||.|:.|...|.||..:..::|:..:|.|.|::..:|| :.|.  |..|||.||:
 Worm   372 RDDILLKGKKIPTGTLVFAQIWSVLKNDPVFEESSKFNPDRYLMADGKTINKSVLERTIPFSVGK 436

  Fly   464 RMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNV------GATITPESFKVCLKRRPL 522
            |.|:|:.||||||||.|::.:..::.       :|  |.|:      ||.:|.:.: :|    .|
 Worm   437 RNCVGEGLARMELFLIFSALIQKYEF-------IP--KTNIDVKPVCGAVLTTKPY-IC----EL 487

  Fly   523 GPTAA 527
            .|.||
 Worm   488 VPQAA 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	147/487 (30%)
cyp-14A2	NP_510204.1	p450	27..484	CDD:278495	147/485 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720