Protein Alignment Cyp18a1 and cyp-14A1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_510203.1
• Gene: cyp-14A1 / 187183
• WormBaseID: WBGene00010705
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 144/514 - (28%)
• Similarity: 255/514 - (49%)
• Gaps: 51/514 - (9%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYL-LFMGSEKHTRFMELAKQYGSLFST 90
            :.||: |..::.::.::...|.::.|.|.||..||.||.: .|........|..|:|.||..|:.
 Worm     1 MSVFI-LAFVIFIIFYVFHFYWKVSKYPKGPLPLPFIGNIHQFPPDNVQKYFDVLSKTYGPCFTI 64

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGR----PDTPFMQTLNGYGIINSTGKLWKDQRRFLHD 149
            .:... .:|::||:.|::.|  :.:.||.|    |:| .:...:..||:.|.|..|:.|||....
 Worm    65 WIPFP-AIVLTDYEHIKDAFVNQGDTFTYRAHRSPET-LLPVHDHTGILASDGDHWRLQRRTSLK 127

  Fly   150 KLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL-HASDGQPVDMSPVISVAVSNVICSLMMSTRFS 213
            .||.||:     |:..|:::::..|||.:..| :.:|.:.||:...|.:.|.|||...:....:.
 Worm   128 ILRDFGL-----GRNLMEEQVIRSVHEMLIQLENINDKKNVDVFWPIQLCVGNVINETLFGFHYK 187

  Fly   214 IDD-PKFRRFNFLIEEGMR-LFGEIH-TVDYIPTMQCFPSI-STAKNKIAQNRAEMQRFYQDVID 274
            .:| .||:.|..::::.:| |.|::. .|...|.::..|.: ....:.|..|.:....|.::.:.
 Worm   188 YEDSEKFKTFVKIVDKHLRHLQGKMPLLVSAFPWLKHVPIVGDIGYHNIKNNISSYHTFIEEEVA 252

  Fly   275 DHKRSFD----PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKT 335
            ...:.:|    |.|   .|..|:.::::....|.|.         ..|...::|.:.|||||...
 Worm   253 TQVKKYDGESEPEN---FVHAYMQQMKQTGNPGLDI---------TNLCATVLDFWLAGMETTSN 305

  Fly   336 TLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHS 400
            :|.|...||::.|:...:|:.|:...||..|||::.|...:|.|::.|.|..|.|:::|...:|.
 Worm   306 SLRWHLAFMMKYPEVQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPFLGSHQ 370

  Fly   401 PTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKP---EYFIPFGVG 462
            ...:.|::|..:||||.|...:.||..:..::|.||.|.|||::.::||....   |..|||.:|
 Worm   371 CKEETEIHGNRVPAGSLVFAQLWSVMRNDTVFEDPETFNPSRYLQSDGKTFDKAVLEKTIPFSIG 435

  Fly   463 RRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRP 521
            :|.|:|:.||||||||.|::.:..::..         ...|:  .:||: :.|.|..:|
 Worm   436 KRNCVGEGLARMELFLIFSALIQKYEFV---------ATSNI--DLTPD-WGVVLTAKP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	124/447 (28%)
cyp-14A1	NP_510203.1	CYP1_2-like	59..485	CDD:410710	127/455 (28%)