Protein Alignment Cyp18a1 and cyp-35B2

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_504094.1
• Gene: cyp-35B2 / 187093
• WormBaseID: WBGene00019471
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 494
• Identity: 130/494 - (26%)
• Similarity: 243/494 - (49%)
• Gaps: 49/494 - (9%)

  Fly    33 LLALVTLLQWLV-RNYRELRKLPPGPWGLPVIG----YLLFMGSEKH-TRFMELAKQ-YGSLFST 90
            :|.|.||:.:|| |.|::.:||||||..||:||    .:.::..||. ....:|.:| ||.:|:.
 Worm     4 ILLLTTLIAFLVARQYQKAKKLPPGPVSLPLIGNIPQLVYYIWREKGVVPAFDLFRQIYGDVFTI 68

  Fly    91 RLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTP-FMQTLNGYGIINSTGKLWKDQRRFLHDKLR 152
            .||....|.:.||...:|.|.:  .....|...| |:...|..|::::.|::|.:.|||.....|
 Worm    69 WLGPIPHVSICDYDTSQEVFVKNGSRLIDRFLPPVFLHLSNNLGLVSANGEVWAEMRRFTLLAFR 133

  Fly   153 QFGMTYMGNGKQQMQKRIMTEVHEFIGHLHAS--DGQP-VDMSPVISVAVSNVICSLMMSTRFSI 214
            ..|:     |:..|::||:.|:......:.|.  :|:. |..|....:||.::|.:.::..||:.
 Worm   134 NIGV-----GRDSMEERILEELDARCEEIDADAVNGKTVVQTSDFFDLAVGSIINNTLIGKRFNA 193

  Fly   215 -DDPKFRRFNFLIEEGMRLF------GEIHTVDYIPTMQCFPSISTAKNKIAQ--NRAEMQRFYQ 270
             :..:|.:...:::....||      ..:..:..:...:| ..|...:.:|..  :|...:|:.|
 Worm   194 HNKDEFMKLKKMMDSASDLFTIFDLTAPVWMLKILVPKRC-ERILGVQEEILNFVSREANERYEQ 257

  Fly   271 DVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEG--TDAELFDGKNHEEQLVQVIIDLFSAGMETI 333
              :...:.:.:..|..|.|:.|..::|:.|..|  |...:       :.|..||.||:.||.:|.
 Worm   258 --LKSGEYTVNAENPHDFVEAYFAKMEEEKRHGGPTPYTM-------KCLKHVIGDLWLAGQDTT 313

  Fly   334 KTTLLWINVF--MLRNPKEMRRVQDELDQVVGRHRLP-TIEDLQYLPITESTILESMRRSSIVPL 395
            .|||  ::.|  ::.:|:.:|:.::|:.::......| .::|........:||.|..|.:||:.:
 Worm   314 TTTL--VSGFNQLVNHPEVIRKCREEILRITENGSRPLQLKDRAESHYLNATITEIQRHASILNV 376

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFG 460
            ...........:.||.|.:|:.:...:.::|::.::::..::|.|.|||: .||:.  ...||||
 Worm   377 NFWRLINEPTNVKGYEIDSGTVMTAQLGALHVNNDIFKNADKFYPERFIE-NGKLL--NQVIPFG 438

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPS 499
            :|:|.|:|:.|||.||:|...:.:..::|. |.|. |||
 Worm   439 IGKRSCVGENLARSELYLLTGNLLLRYNIR-PHGS-LPS 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	107/435 (25%)
cyp-35B2	NP_504094.1	CYP1_2-like	63..492	CDD:410710	107/435 (25%)