Protein Alignment Cyp18a1 and cyp-35B3

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_504095.1
• Gene: cyp-35B3 / 187092
• WormBaseID: WBGene00019470
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 143/499 - (28%)
• Similarity: 244/499 - (48%)
• Gaps: 57/499 - (11%)

  Fly    33 LLALVTLLQWLVRNYREL-RKLPPGPWGLPVIG------YLLFMGSEKHTRFMEL-AKQYGSLFS 89
            |:.:.|||.:|:....:| :||||||...|:||      |.::. :|.....::| .|.||::|:
 Worm     4 LIFITTLLTFLIVRQNQLSKKLPPGPIAFPIIGNIPQVAYYVWK-TEGMVPALDLFRKTYGNVFT 67

  Fly    90 TRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTP-FMQTLNGYGIINSTGKLWKDQRRFLHDKL 151
            ..||....|.:.||:..:|.|.:  .:|..|...| |:......|::.:.|..|.:.|.|.....
 Worm    68 IWLGPIPHVSICDYETSQEVFVKNGNKFKDRLLPPIFIHVSENLGLLTANGDSWAEMRGFTLLAF 132

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHAS--DGQP-VDMSPVISVAVSNVICSLMMSTRFS 213
            |.     ||.||..|:|||:.|::.....:.|.  :|:. |.:|....:.|.:||.|.::..||.
 Worm   133 RN-----MGVGKDLMEKRILDELNARCAEIDADAVNGKTIVKISDFFDLTVGSVINSTLVGKRFE 192

  Fly   214 I-DDPKFRRFNFLIEEGMRLFGEIH-TVDYIPTMQCFPSISTAKNKIAQ------NRAEMQRFYQ 270
            . :..:|.....:|.....:|.... ||........||.......:|.:      :|...:|:.:
 Worm   193 AHNKDEFLHLKKIIHVSSDIFTTFDMTVPVWVLKTFFPGRFARSVEIQEEVLKYVSREASKRYDK 257

  Fly   271 DVIDDH-KRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQ--LVQVIIDLFSAGMET 332
            ..:.:: ..|.||   :|.|:.:|.:|::.:..|       |..|...  |.|||.||:.||.:|
 Worm   258 MKLGEYTPSSEDP---QDFVEAFLAKIDQEEQTG-------GPTHFTMRCLNQVIADLWLAGQDT 312

  Fly   333 IKTTLLWINVF--MLRNPKEMRRVQDELDQVV-GRHRLPTIEDLQYLPITESTILESMRRSSIVP 394
            ..|||  ::.|  ::.||:.||:.::|:.::. ..:|...::|........:||.|..|.:||:.
 Worm   313 TATTL--VSGFNQLVNNPEVMRKCREEIMKITENGYRPLQLKDRAETHYLNATIAEIQRHASILN 375

  Fly   395 L---ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYF 456
            :   ...|.||   .:|||.|.||:.:...:.::|::.::::.|.:|.|.|||: .||:.  ...
 Worm   376 VNFWRLVHEPT---IVNGYEIDAGAVITSQLGALHVNNDIFKDPSKFYPERFIE-NGKLL--NQI 434

  Fly   457 IPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSL 500
            ||||:|:|.|:|:.:||.||:|...:.:..:||. |.|. ||||
 Worm   435 IPFGIGKRSCVGENIARSELYLMIGNLLLRYDIK-PHGS-LPSL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	123/439 (28%)
cyp-35B3	NP_504095.1	CYP1_2-like	63..492	CDD:410710	123/439 (28%)