Protein Alignment Cyp18a1 and cyp-33D1

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_507076.1
• Gene: cyp-33D1 / 187025
• WormBaseID: WBGene00010589
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 159/514 - (30%)
• Similarity: 267/514 - (51%)
• Gaps: 45/514 - (8%)

  Fly    28 MVFLGLLALVTL-----LQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSL 87
            |:.|.:.:|:.|     ..|..|||      ||||..||::|.||.:....:..|.:..|::|.:
 Worm     1 MLLLLISSLIFLFFAYHFSWKRRNY------PPGPTPLPLVGNLLQLQKFGYDIFHKWKKEFGPV 59

  Fly    88 FSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLN---------GYGIINSTGKLWKDQ 143
            |:..|..:..:.::.|::::|.|.::     .||...:.||         .||::::.|::|::.
 Worm    60 FTFWLADRPFIFITSYEVMKETFVKD-----GDTFADKQLNQIDKKKLQRNYGVLDTNGEMWREH 119

  Fly   144 RRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMM 208
            |||...:||..|:     ||..||::|:.|:.|....:::..|:.:|:..|:...|.|||...:.
 Worm   120 RRFTLSQLRDLGL-----GKDLMQEKILLEIEEQFKDINSHLGEEIDLPSVLDRGVGNVINLTLF 179

  Fly   209 STRFSIDD-PKFRRFNFLIEEGMR-LFGEI-HTVDY-IP-TMQCFPSISTAKNKIAQNRAEMQRF 268
            :.||..:. .:|.....|| :|:| :..|. :.:.: :| :.:..|. .|..:|....:.|:..|
 Worm   180 NKRFETNQRDEFTYLKSLI-DGLRDVASEFRYFIQFLVPWSSKIIPG-PTLGDKTKGMKEELDVF 242

  Fly   269 YQDVIDDHKRSFDPNNIR--DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGME 331
            :...:::|::..|.:.:.  |.|:.||.|.:|.:|:| |.|.|..|    ||..:..||:.||::
 Worm   243 FVKQVEEHRKEIDFDTVESYDYVEAYLKEQKKREADG-DHETFCNK----QLYAMCFDLWMAGLQ 302

  Fly   332 TIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLA 396
            |...||.|...|.|.|.....::::|||:|:|..||.|..|...||...:.|.|:.|.::|:|..
 Worm   303 TTTVTLTWGFSFYLHNADVQLKIREELDRVIGNDRLITTADKNCLPYLTAFINETQRCANIIPFN 367

  Fly   397 TTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGV 461
            ..|..|||..:.||.:..|:.||..|.:|..|..::.....|.|.|||: .||::|.:..|||.:
 Worm   368 LLHVATRDTVIEGYPVKKGTGVIAQIGTVMSDEQIFPDAHCFNPGRFIE-NGKLKKVDEVIPFSI 431

  Fly   462 GRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            |:|.|||:.|||||||||||:..:.:|:.|.....||.|..:....:||..|...|.:|
 Worm   432 GKRQCLGEGLARMELFLFFANIFNRYDVQLDFSGNLPDLDKSKDNFVTPRKFNAVLNKR 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	149/478 (31%)
cyp-33D1	NP_507076.1	p450	26..482	CDD:278495	148/473 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I1197
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I1894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm14091
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770