Protein Alignment Cyp18a1 and cyp-33E2

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_501470.2
• Gene: cyp-33E2 / 185653
• WormBaseID: WBGene00018334
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 168/513 - (32%)
• Similarity: 274/513 - (53%)
• Gaps: 39/513 - (7%)

  Fly    26 LLMVFLGLLA--LVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSE---KHTRFMELAKQYG 85
            :|.:.|.:::  |..|..|..||      |||||..||::|.|..|..:   .::.|..|.:|||
 Worm     2 ILFIVLSIVSIYLFDLFYWKRRN------LPPGPLPLPLVGNLHMMSDDVKPGYSLFSNLKEQYG 60

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL--NGYGIINSTGKLWKDQRRF 146
            .:::..:.|...|.::|:.:|::.|.::  .|.|||:.|....|  ..||||.|.|..|..||||
 Worm    61 HVYTFWMASLPIVHVTDWNLIKQHFIKDGGNFVGRPEFPMSIELRQGPYGIIESHGDRWVQQRRF 125

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            ....||.||:     ||..|:::::.||...:..|..:..: |||..|...:|.:||.:|:...|
 Worm   126 ALHVLRDFGL-----GKNLMEEKVLGEVTAMLDRLRKTMDE-VDMQSVFDASVGSVINNLLFGYR 184

  Fly   212 FSIDDPKFRRFNFLIEE-------GMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFY 269
            :  |:.....|..|.|:       ..:..|.:  :...|.:..||..|..||.:.||...:...:
 Worm   185 Y--DETNIAEFLDLKEKLNNHFQLAAKPIGGL--IGMNPWLGYFPYFSGYKNVMIQNWMGLVEMF 245

  Fly   270 QDVIDDHKRSFD--PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMET 332
            :...::...:.|  .::..|.|:.:|.|.:|.:.|    :.|.| ...|||..|..||:.|||||
 Worm   246 RKQANEKLATIDYESDDYSDYVEAFLKERKKHENE----KDFGG-FEMEQLDSVCFDLWVAGMET 305

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLAT 397
            ...||.|..:::||||:..::|.:|||:.:|..|:.|..|...|....:||.||.|.::::|:..
 Worm   306 TSNTLNWALLYVLRNPEVRQKVYEELDREIGSDRIITTSDKPKLNYINATINESQRLANLLPMNL 370

  Fly   398 THSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVG 462
            ..|.|:|||:.||.|...:.:||.|:.|..:|.::.:|.||:|.||::::|.::|.|..:||.:|
 Worm   371 ARSTTKDVEIAGYHIKKNTVIIPQISLVLYNPEIFPEPYEFKPERFLESDGSLKKVEELVPFSIG 435

  Fly   463 RRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            :|.|.|:.||:|||.||||:..:.|||.|.:..|.||::...|.|:..:|:::.||.|
 Worm   436 KRQCPGEGLAKMELLLFFANLFNRFDIQLHQSNPNPSVEKEFGVTMKAKSYRLKLKDR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	157/478 (33%)
cyp-33E2	NP_501470.2	p450	35..490	CDD:278495	151/469 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I1197
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I1894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm14091
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770