Protein Alignment Cyp18a1 and cyp-33C6

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001303728.1
• Gene: cyp-33C6 / 185591
• WormBaseID: WBGene00018264
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 517
• Identity: 158/517 - (30%)
• Similarity: 262/517 - (50%)
• Gaps: 49/517 - (9%)

  Fly    28 MVFLGLLALVTL-----LQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK--HTRFMELAKQYG 85
            |:.|.|.|.|.:     |.|      :.|.|||||..||.:|.:|.:..||  :..|....||:|
 Worm     1 MIILLLSAAVCVFLFHELFW------KRRHLPPGPTPLPFMGNILAVILEKPGYECFRRWTKQFG 59

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLNG--YGIINSTGKLWKDQRRF 146
            .:::..:|:...:::..|.:::|.:.|  :.:..:...||.:.|.|  |||:.|.|.||...|:|
 Worm    60 DVYTFWMGNTPYIIIGTYDLLKETYIRDGDTYKDKYPHPFNEQLRGGMYGIVESNGHLWSTHRKF 124

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            ....||.||:     ||..||:.|:.||.:......|..|:..::..|:..|::|||..::...|
 Worm   125 ALSTLRNFGL-----GKDLMQENILIEVEDIFRKFDAQLGKEQEIQVVLKNAIANVINQIIFGYR 184

  Fly   212 F-SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCF----------PSISTAKNKIAQNRAEM 265
            | :.:..|..:..:|:|...:.|..:..     ::|.|          .|:....|:...|   .
 Worm   185 FDATNQDKLEKMRYLVEYQEKAFTTVKA-----SIQAFAPRIGSILPGKSLDQLLNEFKDN---F 241

  Fly   266 QRFYQDVIDDHKRSFDPNN--IRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSA 328
            ..|:...|::|:|..|.::  .:|..:.||.|..|.:|.| :.|||.    ..|.....:||:.|
 Worm   242 YTFFNAEIENHRRKIDVDSEESQDYAEAYLKEQRKHEARG-EFELFS----NTQFANTCLDLWLA 301

  Fly   329 GMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIV 393
            |:.|..||:.|...::|.:|:.::::.:|.|||||..||.::.|...||...:.:.||.|.::||
 Worm   302 GVSTTNTTVNWTICYVLNHPEVLQKMNEEFDQVVGSDRLVSMGDKNNLPYFNAVLNESQRCANIV 366

  Fly   394 PLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIP 458
            .:...|:.|:|..:|||.|..|:.||..|::|.:|..::.:|.:|.|.|||...||..|.|..||
 Worm   367 TINLFHATTKDTVINGYPIKKGTGVIAQISTVMLDEKIFPEPYKFNPDRFIGENGKPIKIEQLIP 431

  Fly   459 FGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            |.:|:|.|.|:.|||||:||..|:..:.:.|: |..:..|:|:.|....|..:..:|.|.:|
 Worm   432 FSIGKRQCPGEGLARMEIFLLVANLFNRYKIS-PFSEGFPNLEKNSVVEIFAKGLRVILTKR 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	147/481 (31%)
cyp-33C6	NP_001303728.1	p450	26..478	CDD:278495	145/470 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I1197
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I1894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm14091
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.770