Protein Alignment Cyp18a1 and cyp-35D1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_507044.1
• Gene: cyp-35D1 / 184495
• WormBaseID: WBGene00008829
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 128/523 - (24%)
• Similarity: 247/523 - (47%)
• Gaps: 75/523 - (14%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMEL------AKQY 84
            |:::||..:.::|     ||.||::.:.||||:.||:||....:..:...|...|      .|:|
 Worm     3 LILLFLTAITVIT-----VRLYRKVLRFPPGPFPLPLIGNAHQIAYQAWRRGGILPALDYYRKKY 62

  Fly    85 GSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQ-TLNGYGIINSTGKLWKDQRRF 146
            |:.::..||.:.:|.::|::..:|.|.::  :...|...|.:: ...|.|::.:.|:.|.:.|||
 Worm    63 GNAYTLWLGPKASVSITDFETSQEVFVKQGKKCYNRQLAPILEHVTGGVGLLIANGENWAEMRRF 127

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVH----EFIGHLHASDGQPVDMSPVISVAVSNVICSLM 207
            .....||     ||.|...|:||||.|::    |....:..:|...||:. ...:.|.:||.|.:
 Worm   128 TLLTFRQ-----MGVGTNIMEKRIMDELNGRCLEIDAQIARNDRAIVDVK-FFDLTVGSVINSFL 186

  Fly   208 MSTRFSIDDPKFRRFNFLIEEGMRLFG--EIHT-VDYIPTMQCFPSISTAKNKIA-QNRAEMQRF 268
            :..||. |:.:|.:...|.:|....|.  :::. |.::.|.  .||    :.|:. .:|.::...
 Worm   187 IGKRFE-DEEEFLKIKKLFDESSETFNIFDLNVPVWFLKTF--LPS----RFKLTWDSRHQIMDH 244

  Fly   269 YQDVIDDHKR-------SFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKN---HEEQLVQVII 323
            ....:::..|       ..||....|:||.:|.:::|      :.|:..|::   :.:.|..|:.
 Worm   245 VMKGVEERIRDIESGAYKIDPKKPNDVVDAFLSKMKK------EEEIAGGQHPYYNLKSLKLVLH 303

  Fly   324 DLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVV--GRHRLPTIEDLQYLPITESTILES 386
            ||:.||..|..|||....:.::.:|..::.:|.||..:.  |...| |::|....|...:||.|.
 Worm   304 DLWLAGQGTTATTLYVGFMKLVNHPGIIQNIQKELLDITENGARDL-TLKDRPNTPYLNATIAEI 367

  Fly   387 MRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVR 451
            .|.:||:.:.........:..|.|.:..|:.:...:..:|::..|::.|::|...:::      :
 Worm   368 QRHASILNVNFWRINHETIHFNDYQVDPGTMIAAQVGVLHVNEELFDNPKDFNVEKYL------K 426

  Fly   452 KP---EYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQP------------LPSLK 501
            .|   :..||||:|:|.|:|:.:|:.||:|.|.:.:..:::......|            ||.:.
 Worm   427 NPKLLQQVIPFGIGKRSCVGEQIAKSELYLVFGNILLRYNVKKHGSTPTNEDVYPYSSAKLPDVS 491

  Fly   502 GNV 504
            |.:
 Worm   492 GKL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	108/458 (24%)
cyp-35D1	NP_507044.1	CYP1_2-like	63..489	CDD:410710	106/451 (24%)