Protein Alignment Cyp18a1 and cyp-33E1

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_501480.2
• Gene: cyp-33E1 / 183602
• WormBaseID: WBGene00016768
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 170/511 - (33%)
• Similarity: 273/511 - (53%)
• Gaps: 43/511 - (8%)

  Fly    33 LLALVTLLQWLVRN--YRELRKLPPGPWGLPVIGYLLFMGSE---KHTRFMELAKQYGSLFSTRL 92
            ||.|.::|...:.|  |.:.|||||||..||:||.|..|..:   .:..:.:|..:||.:|:..|
 Worm     3 LLILTSILIIYLFNHFYWKRRKLPPGPIPLPIIGNLYLMTEDVKPGYKMYEKLKDKYGPVFTFWL 67

  Fly    93 GSQLTVVMSDYKMIRECFRRE--EFTGRPDTPF-MQTLNG-YGIINSTGKLWKDQRRFLHDKLRQ 153
            .:...|.::|:|:|::.|.::  .|.|||:.|. |:...| ||||.|.|..|..||||....||.
 Worm    68 ANLPMVTVTDWKLIKQHFIKDGANFVGRPEFPISMEMRQGPYGIIESHGDRWIQQRRFALHILRD 132

  Fly   154 FGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPK 218
            ||:     ||..|:::::.||...|..:..| .:.|||..:...:|.:||.:::...|:  |:..
 Worm   133 FGL-----GKNLMEEKVLGEVTAMIDSIRKS-MEDVDMQNIFDASVGSVINNMLFGYRY--DETN 189

  Fly   219 FRRFNFLIEEGMRLFGEIH------------TVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQD 271
                   |||.:.|...::            .:...|.:...|.....||.|..|...:...::.
 Worm   190 -------IEEFLELKNRMNKHFKLAAEPMGGLIGMNPWLGHLPFFKGYKNVIMHNWMGLMEMFRK 247

  Fly   272 VIDDHKRS--FDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIK 334
            ...|...|  :|.:...|.|:.:|.|.:|.:.|    :.|.| ...|||..|..||:.|||||..
 Worm   248 QATDRLASIDYDSDEYSDYVEAFLKERKKHENE----QDFGG-FEMEQLDSVCFDLWVAGMETTS 307

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            .||.|..:::|.||:..::|.:||::.:|..|:.|..|...|....:|:.||.|.::::|:..:.
 Worm   308 NTLNWALLYVLLNPEVRQKVYEELEREIGSDRIITTTDRPKLNYINATVNESQRLANLLPMNLSR 372

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRR 464
            |...|||:.||.||..:.:.|.|:||..||.::.:|.||:|.||::::|.::|.|..:||.:|:|
 Worm   373 STNADVEIAGYRIPKDTVITPQISSVMYDPEIFPEPYEFKPERFLESDGSLKKVEELVPFSIGKR 437

  Fly   465 MCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            .|||:.||:|||||:||:..:.|||...|..|.||:|..||.|:..::::|.:|.|
 Worm   438 QCLGEGLAKMELFLYFANLFNKFDIKFHESNPNPSIKKEVGVTMKAKNYRVSMKER 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	159/483 (33%)
cyp-33E1	NP_501480.2	p450	49..490	CDD:278495	149/460 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I1197
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I1894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm14091
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770