Protein Alignment Cyp18a1 and cyp-36A1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_492267.1
• Gene: cyp-36A1 / 183193
• WormBaseID: WBGene00007913
• Length: 493
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 154/516 - (29%)
• Similarity: 249/516 - (48%)
• Gaps: 46/516 - (8%)

  Fly    28 MVFLGLLALVTLLQ-WLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFM-ELAKQYGSLFST 90
            |:|..|:.||.::. :|.|...:||.|||||...|.||....:..::....: |..|:||.:|:.
 Worm     1 MLFAQLVILVIIVMLFLCRFANKLRGLPPGPTPWPFIGNTFQVPEDRIDLIINEFKKKYGGIFTL 65

  Fly    91 RLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTL--NGYGIINSTGKLWKDQRRFLHDKL 151
            .|... |:|:.||.|::....:  |.|:|||||..|..|  ..||:.......||.||||.....
 Worm    66 WLPFP-TIVICDYDMLKRNIVKNGESFSGRPDTFIMDMLVQGNYGLFFMENNWWKAQRRFTTHIF 129

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            |..|:     |:...|..|.:.....:..:.....:|:::.|::...|.|||...:.......::
 Worm   130 RSLGV-----GQAGTQDTIASLASGLVEKIDGQKDKPIELRPLLVHVVGNVIHKHLFGFTREWNE 189

  Fly   217 PKFRRFNFLIEEGMRLFGEIHT--------VDYI--PTMQCFPSISTAKNKIAQNRAEMQRFYQD 271
            .:...|:..|.:.:..|....|        :.|:  |.....|..:.|.:.|.||       .:.
 Worm   190 TEILDFHVAINDVLEHFTSPKTQLLDAWPWLAYLDKPLSLGIPRTTRANDAIIQN-------LEQ 247

  Fly   272 VIDDHKRSF----DPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMET 332
            .:..||...    :|::   .:|.:|.|::...||..   |.||.. |:||:..|.||:||||||
 Worm   248 ALAKHKTGINYDEEPSS---YMDAFLKEMKIRAAENA---LEDGFT-EKQLIVAIYDLYSAGMET 305

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLAT 397
            |...|.:..::::.||:..:|:.:|||:.|||.|...::|.::||.|.:.:.|..|...::|:..
 Worm   306 IIIVLRFAFLYLVNNPETQKRIHEELDRNVGRERQVVMDDQKHLPYTCAFLQEVYRLGYVLPVNF 370

  Fly   398 THSPTRDVE-LNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGV 461
            ......||| ..||.:.||:.||....|||:|...:..||.|.|.||:::.|:..:.:...||.:
 Worm   371 LRCTLTDVEDCEGYRLNAGTRVIAQFQSVHVDKKHFPDPEHFNPDRFLNSRGEYIRDDRVNPFSM 435

  Fly   462 GRRMCLGDVLARMELFLFFASFMHCFDIAL--PEGQPLPSLKGNVGATITPESFKVCLKRR 520
            |:|.|||:.|||||:||:|.:.|..|:...  |...|:..:..::.|   |:.|.|...||
 Worm   436 GKRSCLGENLARMEVFLYFCTLMQNFEWHTDGPYAPPIDVITSSLRA---PKPFTVRASRR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	131/450 (29%)
cyp-36A1	NP_492267.1	CYP1_2-like	60..488	CDD:410710	131/450 (29%)