Protein Alignment Cyp18a1 and cyp-35A2

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_504880.2
• Gene: cyp-35A2 / 182177
• WormBaseID: WBGene00015400
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 493
• Identity: 141/493 - (28%)
• Similarity: 238/493 - (48%)
• Gaps: 71/493 - (14%)

  Fly    29 VFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIG-------YLLFMGSEKHTRFMEL-AKQYG 85
            :|..|...|.|...:||.|:::.:|||||..||:||       ||...|....|  ::| .|:||
 Worm     1 MFFVLFFSVLLGYLIVRQYQKVSRLPPGPISLPLIGNLPQIIYYLWSTGGIVST--LDLFRKRYG 63

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFL 147
            ::|:..:|....|.::||:...|.|.:.  ::..:...|.|:.: |..|::.:.|..|::.|||.
 Worm    64 NIFTLWVGPIPHVSIADYETSHEVFVKNAGKYADKFHAPVMRDVRNDIGVLITNGDHWQEMRRFS 128

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLH--ASDGQPV-DMSPVISVAVSNVICSLMMS 209
            ....|.     ||.||..|:.|||.|:......:.  |::|..: ..|....:.|.::|.|:::.
 Worm   129 LQAFRN-----MGVGKDIMETRIMEELDARCSDIDKLATNGVTITHASEFFDLTVGSIINSILVG 188

  Fly   210 TRFSIDDP-KFRRFNFLIEEGMRLFGEI--------------HTVDYIPTMQCFPSISTAKNKIA 259
            .||..|.. :|.:....::.....|...              |..|.|.:.|     .||||..|
 Worm   189 KRFEEDTKHEFLKIKETMDASFETFSPFDMTAPVWFLKTFFKHRYDKIWSAQ-----ETAKNFAA 248

  Fly   260 Q---NRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQV 321
            .   .|.|..:..:.|||:       ||::|..|.:|.:|:| :.|..|..:       |.|..:
 Worm   249 AEAIKRVESIKSGKYVIDE-------NNLQDYTDAFLLKIQK-EGESKDFNI-------ETLKTM 298

  Fly   322 IIDLFSAGMETIKTTLLWINVF--MLRNPKEMRRVQDELDQVV---GRHRLPTIEDLQYLPITES 381
            ||||:..|.||..|||  |:.|  :|.:|:.|.:.::|:.::.   .||.  ::.|....|...:
 Worm   299 IIDLWMTGQETTTTTL--ISGFNQLLLHPEVMIKAREEILKITENGSRHL--SLTDRTSTPYVNA 359

  Fly   382 TILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDT 446
            .|.|..|.:||:.::..........:.|:.:.||:.|...::::|::..:::.|:||.|.||| .
 Worm   360 VIGEIQRHASILNVSFWKINKEFTYMGGHPVDAGALVTSQLSALHVNETVFKNPQEFNPERFI-R 423

  Fly   447 EGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFM 484
            :||:.  :..||||||:|.|||:.||:.||:|.|.:.:
 Worm   424 DGKLL--QKVIPFGVGKRNCLGESLAKAELYLIFGNLL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	118/429 (28%)
cyp-35A2	NP_504880.2	CYP1_2-like	63..489	CDD:410710	118/429 (28%)