Protein Alignment Cyp18a1 and cyp-35A1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001343612.1
• Gene: cyp-35A1 / 182176
• WormBaseID: WBGene00015399
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 138/496 - (27%)
• Similarity: 231/496 - (46%)
• Gaps: 76/496 - (15%)

  Fly    26 LLMVFLGLLALVTLLQWL-VRNYRELRKLPPGPWGLPVIG-------YLLFMGSEKHTRFMEL-A 81
            |:::||.|..      || :|.|:::.:|||||...|:||       ||...|....|  ::| .
 Worm     3 LVLIFLALSC------WLIIRQYQKVSRLPPGPVSFPIIGNLPHIIYYLWATGGIVST--LDLFR 59

  Fly    82 KQYGSLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTP-FMQTLNGYGIINSTGKLWKDQ 143
            |:||::|:..:|....|.:.||:...|.|.:  .::......| |.:.....|::.:.|..|...
 Worm    60 KKYGNIFTLWVGPVPHVSICDYETSHEVFVKGANKYADIAHAPLFRELRQEMGVLVTNGSHWSTM 124

  Fly   144 RRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL--HASDGQPV-DMSPVISVAVSNVICS 205
            :||.....|.     ||.||..|:.|||.|:.......  .|:||..| .......:.|.::|.|
 Worm   125 KRFALHTFRD-----MGVGKDLMETRIMEELDARCADTDKSATDGVTVAQAGDFFDLTVGSIINS 184

  Fly   206 LMMSTRFSIDDPKFRRFNFL-IEEGMRLFGEIHT------------------VDYIPTMQCFPSI 251
            :::..||.    :..:.:|| |:|.|....|:.:                  .|.:.|.|
 Worm   185 ILVGKRFE----EHNKDDFLKIKEAMGAAFEVFSPFDMAVPVWFLRTFFRSRYDMMMTTQ----- 240

  Fly   252 STAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEE 316
            :|||...|   ||..:..:| |.......|.:||.|..|.:|.:|:|   :|.|.:.     :.|
 Worm   241 NTAKRFAA---AEAVKRIED-IKSGAYEIDESNIEDYTDAFLLKIQK---DGEDLDF-----NIE 293

  Fly   317 QLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVV---GRHRLPTIEDLQYLPI 378
            .|..:||||:..|.||..|||:.....:|.:|:.|.:.::|:.::.   .||.  ::.|....|.
 Worm   294 TLKTMIIDLWMTGQETTTTTLISGFTQLLLHPEVMVKAREEILKITENGSRHL--SLTDRTSTPY 356

  Fly   379 TESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRF 443
            ..:.|.|..|.:||:.::..........:.|:.:.||:.|...::::|::..:::.|:||.|.||
 Worm   357 LNAMIGEIQRHASILNVSFWKINKELTYMGGHPVDAGALVTAQLSALHVNDTIFKNPQEFDPERF 421

  Fly   444 IDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFM 484
            |..|..::|   .||||||:|.|:|:.|||.||:|...:.:
 Worm   422 IRDEELLQK---VIPFGVGKRSCIGESLARAELYLIIGNLL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	115/428 (27%)
cyp-35A1	NP_001343612.1	CYP1_2-like	63..489	CDD:410710	115/428 (27%)