Protein Alignment Cyp18a1 and cyp-34A8

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_504102.2
• Gene: cyp-34A8 / 181850
• WormBaseID: WBGene00015043
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 153/520 - (29%)
• Similarity: 244/520 - (46%)
• Gaps: 56/520 - (10%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIG------YLLFMGSEKHTRFMELAKQY 84
            |:::.|.:.|::|...|..|     :|||.||..||:||      ||.:........|.||.|||
 Worm     3 LILILLAVAAVLTANLWRAR-----QKLPKGPTPLPLIGNFHQLFYLSWKTGSLVAAFNELKKQY 62

  Fly    85 GSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRF 146
            |.:|:..:|.:.:|.:.||.:..|..  |...|..|.....|:.: .|.|||.|.|..|.:.|||
 Worm    63 GKVFTVWMGPKPSVYICDYDIAHETHVKRANIFGTRYSVGGMEYIREGRGIIGSNGDFWLEHRRF 127

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEV-HEF--IGHLHASDGQ-PVDMSPVISVAVSNVICSLM 207
            ....||.||:     |:..|:.:||.|. :.|  ....|..:|. .|:.|.:..:.|.::|..|:
 Worm   128 ALMTLRNFGV-----GRTIMEDKIMDEYRYRFKDFKRTHFKNGAIQVNASSIFDLLVGSIINQLL 187

  Fly   208 MSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIA----------QNR 262
            :|.||..||.:|.:....:.|.:.....|.  .::|.......:...:.||.          .||
 Worm   188 VSERFEQDDQEFEKLKTSLAEALENISIIE--GFLPLWVLKSPLMKWRTKITFAPFDFIFELGNR 250

  Fly   263 AEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFS 327
            ...:|........|..|.:.:   |.||.::.::||.|.||.|:..     ..|.|...:.||:.
 Worm   251 GIQRRVAAIENGTHTLSEEGD---DFVDAFIVKMEKDKKEGIDSSF-----TLETLAIDLFDLWQ 307

  Fly   328 AGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSI 392
            ||.||..|||.|..|.:|.:|:.:.:::.||.:|.|..|..::.|....|...:.|.|..|.:||
 Worm   308 AGQETTSTTLTWACVCLLNHPEVVEKLRKELTEVTGGTRGVSLTDRTKTPYLNANINEFQRIASI 372

  Fly   393 VPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFI 457
            :.:........|..::...:|||:.|...::.:|.|..:::.|:||||.||::.....::   .|
 Worm   373 LNVNLFRVLEEDTTIDSQPVPAGALVTTNLSMLHTDEEIFKNPQEFRPERFMENNNLEKR---LI 434

  Fly   458 PFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPL 522
            |||:|:|.|.|:.|||.||||...:.:..:|:. |.| .||.::     |.||.:   .:||.|:
 Worm   435 PFGIGKRACPGESLARAELFLITGNMILDYDLE-PVG-TLPKIE-----TTTPFA---PMKRPPV 489

  Fly   523  522
             Worm   490  489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	127/446 (28%)
cyp-34A8	NP_504102.2	CYP1_2-like	63..492	CDD:410710	130/455 (29%)