Protein Alignment Cyp18a1 and daf-9

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_741807.2
• Gene: daf-9 / 180889
• WormBaseID: WBGene00000905
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 145/535 - (27%)
• Similarity: 262/535 - (48%)
• Gaps: 73/535 - (13%)

  Fly     6 YLIKFVLRQL--QVQQDGDAQHLLM-VFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLL 67
            ||:  :||..  ||..|.:.||..| ||     :|.::..::..:..:.:.||||..:.|.|...
 Worm    64 YLL--ILRNFLPQVVPDFEWQHYFMRVF-----IVHIIYIIISYFIRITRYPPGPPPMAVFGNSP 121

  Fly    68 FMG--SEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFM---- 124
            |:.  :.:.| |:|..:.||.:|:..| ||.|:::::||.|:|...:  ::.:||......
 Worm   122 FVNILTPEQT-FLEYREIYGPIFTLHL-SQPTIILAEYKTIQEALVKNGQQTSGRSSAESFVLFT 184

  Fly   125 -QTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLH------ 182
             ..|||.|:|.:..:.|||.|.    ::.:|           |.|.....:.|.:.| |
 Worm   185 GDRLNGDGVILAMRQKWKDMRH----EISRF-----------MNKWYGAPMDELVLH-HTRCLEQ 233

  Fly   183 -----ASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKF----RRFNFLIEEGMRLFGEIHT 238
                 |.....:|:...::.|::|||..:.:...:...|.:|    |..|.:::|.|.  .|:..
 Worm   234 ELAKIAETKSLIDLRDPLAGAIANVIQQITIGRNYMYQDQEFQTQLRDINAVVKEIMT--AEVFF 296

  Fly   239 VDYIPTMQCFP-SISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDF--YLCEIEKAK 300
            |:..|.::..| .|........::...:|::::.::::|..:      |...||  ::.:::::|
 Worm   297 VNCYPWLRYLPEGILRKWTNYKRSGFRLQQWFRTILEEHHVN------RHQGDFMSHMIDLQESK 355

  Fly   301 AEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRH 365
            .|         :..:..::....|:::.||||..|||.|..:::|.||:...:.|.|:..|.| :
 Worm   356 QE---------QFRDLSIILTCGDMWTGGMETTVTTLRWGIIYLLNNPEVQAKCQMEILDVFG-N 410

  Fly   366 RLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPN 430
            .:|.:..:...|...:|:.|..|.::::|.|..|....:..:.||.||..:.:||.:.:|..|||
 Worm   411 DIPDMGKMNQTPYVRATLSEIQRLANVLPWAIPHKTIEECNIGGYDIPVNTEIIPALGAVLFDPN 475

  Fly   431 LWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQ 495
            ::|.|::|:|.||:|.|||.|..|.|.|||:|.|:|||:.:||.||:|.|||.:..|...|..|.
 Worm   476 VFESPKQFKPERFLDEEGKYRVMEEFRPFGLGPRVCLGERIARTELYLIFASLLQNFRFYLNRGD 540

  Fly   496 PLPSLKGNVGATITP 510
            |:|..:..:|....|
 Worm   541 PIPVAERVIGGITAP 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	121/451 (27%)
daf-9	NP_741807.2	CYP1_2-like	140..559	CDD:410710	121/451 (27%)