Protein Alignment Cyp18a1 and cyp-14A5

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_504435.1
• Gene: cyp-14A5 / 178926
• WormBaseID: WBGene00000373
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 505
• Identity: 151/505 - (29%)
• Similarity: 255/505 - (50%)
• Gaps: 44/505 - (8%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLL-FMGSEKHTRFMELAKQYGSLFS- 89
            :.||:..|: |.::.:::..|.::||.|.||:.||..|.|| |..........:|:|.||..|:
 Worm     1 MSVFIVALS-VFIISYVISFYWKVRKYPKGPFPLPFFGNLLQFPADNIQEHLDKLSKTYGPCFTV 64

  Fly    90 -TRLGSQLTVVMSDYKMIRECF--RREEFTGR----PDTPFMQTLNGYGIINSTGKLWKDQRRFL 147
             |.|.:   ||::||:.|:|.|  :.:.|..|    |:..|....| .|::.|:|..||.|||..
 Worm    65 WTPLPA---VVLTDYEHIKEAFVTQGDAFVNRAQRLPEILFQPHPN-TGVVFSSGDNWKIQRRTA 125

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL-HASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            ...||.||:     |:..|::::|..|||.:..| |.||.:.|||...|.:.|.|||...:....
 Worm   126 LKILRDFGL-----GRNLMEEQVMRSVHEMLAQLEHISDKKNVDMYWPIQLCVGNVINESLFGYH 185

  Fly   212 FSIDDP-KFRRFNFLIEEGMRLF-GEIH-TVDYIPTMQCFPSI-STAKNKIAQNRAEMQRFYQDV 272
            :..:|. :|.:|..:::..:::. |... .|...|.::..|.| :...:.|..|....|:|.::.
 Worm   186 YKYEDAGRFEKFVKVVDRHLKIAQGNASLLVSAFPWLRHLPVIGNLGYHSIKNNIKSYQQFIEEE 250

  Fly   273 IDDHKRSFD----PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETI 333
            :....:::|    |.|   .|..|:.::::......|.         ..|...::|.:.|||||.
 Worm   251 VTSQLKNYDGESEPEN---FVHAYMQQMKQTGNPNLDM---------TNLCASVLDFWLAGMETA 303

  Fly   334 KTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATT 398
            ..:|.|...||::.|:...:|::|:.:.:|..|||::.|.|.:|.|::.|.|..|.|::||:..|
 Worm   304 SNSLRWHLAFMMKYPEVQDKVRNEIFENIGTARLPSMSDKQNMPYTQAVIHEVQRCSNMVPILAT 368

  Fly   399 HSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKP---EYFIPFG 460
            |..|.||.:..:.||.|:.:...|.||..:..::|:..:|.|.|::..:||....   |..|||.
 Worm   369 HMNTEDVLVKEHNIPTGTLLFAQIWSVLKNDPVFEENSKFNPDRYLMPDGKTLNKTVLERTIPFS 433

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITP 510
            ||:|.|:|:.||||||||.|::.:..::........|..:.|.| .|:.|
 Worm   434 VGKRNCVGEGLARMELFLIFSALIQKYEFIPKTNVDLKPVYGGV-ITVKP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	144/478 (30%)
cyp-14A5	NP_504435.1	p450	27..484	CDD:278495	144/478 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720