Protein Alignment Cyp18a1 and cyp-33C2

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_503594.1
• Gene: cyp-33C2 / 178695
• WormBaseID: WBGene00016697
• Length: 495
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 168/511 - (32%)
• Similarity: 264/511 - (51%)
• Gaps: 35/511 - (6%)

  Fly    28 MVFLGLLALVTL-----LQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK--HTRFMELAKQYG 85
            |:.:.||.::|:     |.|..||:      ||||..|||.|.||.:.:..  :..|....|:||
 Worm     1 MLIILLLTVLTVYLVYELYWKRRNF------PPGPCPLPVFGNLLSIANPPPGYEAFERWTKKYG 59

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLNG--YGIINSTGKLWKDQRRF 146
            .:::..:|:...::::.:..|:|.:.|  |.:|.:...|.:....|  ||||:|.|..|::.|||
 Worm    60 DIYTFWIGNTPHIMINTWDKIKETYIRDAETYTNKVRLPALDLFRGGEYGIIDSNGATWREHRRF 124

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            ....:|.||:     ||..||:.|:.||.:....|.|..|...|:..|...||:||:..|:...|
 Worm   125 ALSTMRDFGL-----GKNLMQENILMEVQDVFARLDAKLGSETDIPEVFDHAVANVVNQLLFGYR 184

  Fly   212 F-SIDDPKFRRFNFLIEEGMRLFGEIH--TVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVI 273
            | ...:.:::....:||....|||:.|  ....||.:.........:......|.....|:...|
 Worm   185 FVGPKESEYQELKRIIEAPTDLFGKPHMFLAMNIPVIAKLMPEFMYEGPFKDFRDTAFAFFNKQI 249

  Fly   274 DDHKRSFDPNNIR----DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIK 334
            :.|::..|.|::.    |.|:.:|.|.::.::|| |:|.|.    ..||..|.:||:.||:.|..
 Worm   250 EAHRQEVDLNDLNSESTDFVETFLKEQKRRESEG-DSETFS----NVQLSNVCMDLWFAGLNTTT 309

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            .|:.|...::|.:|:...:|.:|:|:|:|..||.|..|...||...:.|.|:.|..:||||...|
 Worm   310 NTITWAISYILHHPEVQDKVHEEMDKVIGSDRLITTADKNDLPYFNAFINEAQRGINIVPLNLQH 374

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRR 464
            :.|||..:||:.||.|:.|:..|::|..:..::..|..|.|.||||..||:::.|...||.||:|
 Worm   375 ATTRDTVINGFKIPKGTGVVAQISTVMNNEEVFPDPHTFNPDRFIDEHGKLKRVEELAPFSVGKR 439

  Fly   465 MCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            .|.|:.|||||||||.|:|::.:.| .|..:..||:..:.||.|.|..|...||||
 Worm   440 SCPGEGLARMELFLFIANFLNRYKI-YPSKEGPPSMDKSNGALIAPRLFSATLKRR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	156/475 (33%)
cyp-33C2	NP_503594.1	p450	26..491	CDD:278495	156/475 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I1197
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I1894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm14091
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.770