Protein Alignment Cyp18a1 and cyp1a

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_571954.1
• Gene: cyp1a / 140634
• ZFINID: ZDB-GENE-011219-1
• Length: 519
• Species: Danio rerio
• Alignment Length: 520
• Identity: 167/520 - (32%)
• Similarity: 264/520 - (50%)
• Gaps: 58/520 - (11%)

  Fly    33 LLALVT--LLQWLVRNYRE-----LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            |:|::|  |:..|:|..|.     |:|| |||..||:||.:|.:|:..|.....::|.||.:|..
Zfish    18 LVAIITICLVYLLMRLNRTKIPDGLQKL-PGPKPLPIIGNVLEIGNNPHLSLTAMSKCYGPVFQI 81

  Fly    91 RLGSQLTVVMSDYKMIRECFRR--EEFTGRPD---TPFMQTLNGYGIINSTGK--LWKDQRRFLH 148
            ::|.:..||:|...:||:...:  |||:|||:   |.|:.  :|..:..||.:  :|:.:|:...
Zfish    82 QIGMRPVVVLSGNDVIRQALLKQGEEFSGRPELYSTKFIS--DGKSLAFSTDQVGVWRARRKLAL 144

  Fly   149 DKLRQFGMTYMGNGKQ---QMQKRIMTEVHEFIGHLHA---SDGQPVDMSPVISVAVSNVICSLM 207
            :.||.|. |..|...:   .:::.|..|....:..||:   :||. .|....|.|:|:||||.:.
Zfish   145 NALRTFS-TVQGKSPKYSCALEEHISNEGLYLVQRLHSVMKADGS-FDPFRHIVVSVANVICGIC 207

  Fly   208 MSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDV 272
            ...|.|.||.:..|...:.:|..::.|..:..|:||.::..|  ||...|.........:|.:.:
Zfish   208 FGRRHSHDDDELVRLVNMSDEFGKIVGSGNPADFIPFLRILP--STTMKKFLDINERFSKFMKRL 270

  Fly   273 IDDHKRSFDPNNIRDLVDFYL--CEIEKAKAEGTDAELFDGKN---HEEQLVQVIIDLFSAGMET 332
            :.:|..:||.:||||:.|..:  ||         |.:|.:..|   .:|::|.::.|||.||.:|
Zfish   271 VMEHYDTFDKDNIRDITDSLINHCE---------DRKLDENSNLQVSDEKIVGIVNDLFGAGFDT 326

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLAT 397
            |.|.|.|..|:::..|:...|:|.|||:.:|:.|.|.:.|...||:.||.|||..|.||.:|...
Zfish   327 ISTALSWAVVYLVHYPEVQERLQRELDEKIGKDRTPLLSDRANLPLLESFILEIFRHSSFLPFTI 391

  Fly   398 THSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEG-KVRK--PEYFIPF 459
            .|..::|..||||.||..:.|......|:.||.||:.|..|.|.||:..:| ::.|  .|..:.|
Zfish   392 PHCTSKDTSLNGYFIPKDTCVFVNQWQVNHDPELWKDPSSFIPDRFLTADGTELNKLEGEKVLVF 456

  Fly   460 GVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPE-----SFKVCLKR 519
            |:|:|.|:|:.:.|.|:|||.|..:.........|:.|         .:|||     ..|.||.|
Zfish   457 GLGKRRCIGESIGRAEVFLFLAILLQRLKFTGMPGEML---------DMTPEYGLTMKHKRCLLR 512

  Fly   520  519
            Zfish   513  512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	154/488 (32%)
cyp1a	NP_571954.1	p450	46..499	CDD:278495	151/476 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920