Protein Alignment Cyp18a1 and Cyp2j5

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_034137.1
• Gene: Cyp2j5 / 13109
• MGIID: 1270149
• Length: 501
• Species: Mus musculus
• Alignment Length: 503
• Identity: 163/503 - (32%)
• Similarity: 269/503 - (53%)
• Gaps: 28/503 - (5%)

  Fly    22 DAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK-HTRFMELAKQYG 85
            :|.||..:.|.::..:.|:. ::|: |..:..|||||.||.:|....:.::: |....:..|:||
Mouse    14 EALHLKTLVLAVVTFLFLIN-ILRS-RHPKNYPPGPWRLPFVGNFFQIDTKQTHLVLQQFVKKYG 76

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLNG-YGIINSTGKLWKDQRRFL 147
            ::||..||....||:|...:|:|.|..  :.|..|..||..:.:.| .|::.|.|:.||:|||..
Mouse    77 NVFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKNGLVVSNGQTWKEQRRLA 141

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRF 212
            ...||.||:     ||:.:::||..|.|..:..:....|||.:....:..||||:|||:....||
Mouse   142 LMALRNFGL-----GKKSLEERIQEETHHLVEAIREEGGQPFNPHLKLINAVSNIICSVTFGERF 201

  Fly   213 SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSIST----AKNKIAQNRAEMQRFYQDVI 273
            ..:|.:|:....|::|.|.|.|......|    ..||.|..    ...||.:|..:::.|...::
Mouse   202 DYEDCQFQELLQLLDETMHLMGSSAGQLY----NGFPCIMKYLPGPHQKIFRNWGKLKLFVSHIV 262

  Fly   274 DDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLL 338
            ..|::.::|:..||.:|.:|.|::|.....|..       :||.|:...:|||..|.||..:||.
Mouse   263 KKHEKDWNPDEPRDFIDAFLIEMQKDPDRTTSF-------NEENLISTTLDLFLGGTETTSSTLR 320

  Fly   339 WINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTR 403
            |..::|...|:....||.|:|:|:|..|..::.|.:.:|.|.:.|.|..|..:||||.::...|.
Mouse   321 WALLYMSSYPEIQENVQAEIDRVIGHKRQVSLSDRESMPYTNAVIHEVQRMGNIVPLNSSREVTV 385

  Fly   404 DVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLG 468
            |.:.||:.:|.|:.::..:.::|.||..|..||.|.|..|:: .|:.:|.|.|:||.:|:|.|||
Mouse   386 DTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVFNPEHFLE-NGQFKKRESFLPFSMGKRACLG 449

  Fly   469 DVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            :.||:.|||:||::.|..|....|..:.| |||..:|..::|.|:::|
Mouse   450 EQLAKSELFIFFSALMQKFTFKPPINEKL-SLKFRMGLILSPASYRIC 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	144/436 (33%)
Cyp2j5	NP_034137.1	CYP2J	75..495	CDD:410755	145/437 (33%)