Protein Alignment Cyp18a1 and Cyp2c38

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_034132.2
• Gene: Cyp2c38 / 13097
• MGIID: 1306819
• Length: 490
• Species: Mus musculus
• Alignment Length: 519
• Identity: 165/519 - (31%)
• Similarity: 262/519 - (50%)
• Gaps: 64/519 - (12%)

  Fly    27 LMVF--LGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFM-ELAKQYGSLF 88
            |:.|  |.|.:|:.|..|..|:.|  .:|||||...|:||..|.:..:...:.: ..:|.||.:|
Mouse     3 LVTFLVLTLSSLILLSLWRQRSRR--GRLPPGPTPFPIIGNFLQIDVKNFNQSLTNFSKTYGPVF 65

  Fly    89 STRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDK 150
            :..|||:..||:..|:.::|..  ..|||:||.:.|..:.: ||.||..|.|..||:.|||....
Mouse    66 TLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINNGLGITFSNGNSWKETRRFTLMT 130

  Fly   151 LRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSID 215
            ||..||     ||:.::.|:..|....:..|..:.|.|.|.:.::|.|..|||||::...||...
Mouse   131 LRNLGM-----GKRNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYK 190

  Fly   216 DPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQ-C--FPSI----STAKNKIAQNRAEMQRFYQDVI 273
            |..|......:.|.:::...       |.:| |  ||.:    ..:.:|:.:|...::.:..:.:
Mouse   191 DKDFLMLMKKLNENVKILSS-------PWLQVCNNFPLLIDYCPGSHHKVLKNFKYIRSYLLEKV 248

  Fly   274 DDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQ-------LVQVIIDLFSAGME 331
            .:|:.|.|..|.||.:|::|.:.::|             ||.||       ||..|.:||:||.|
Mouse   249 KEHQESLDVTNPRDFIDYFLIKQKQA-------------NHIEQAEYSLENLVCTINNLFAAGTE 300

  Fly   332 TIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLA 396
            |..|||.:..:.:::.|....:||:|:|.||||||.|.::|...:|.|::.|.|..|..::||..
Mouse   301 TTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRSPCMQDRSRMPYTDAMIHEVQRFINLVPNN 365

  Fly   397 TTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGV 461
            ..|:.|.|::...|.||.|:.|:..:.||..|...:..||.|.|..|:|..|..:|.:||:.|..
Mouse   366 LPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLDANGNFKKSDYFMTFSA 430

  Fly   462 GRRMCLGDVLARMELFLFFA---------SFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            |:|:|.|:.||||||||...         |.:|..||.:     :|.:.|.:  |:.|. :::|
Mouse   431 GKRVCAGEGLARMELFLILTTILQNFKLKSLVHPKDIDM-----IPFVNGLI--TLPPH-YQLC 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	155/490 (32%)
Cyp2c38	NP_034132.2	p450	30..487	CDD:278495	155/490 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm43796
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820