Protein Alignment Cyp18a1 and Cyp2c29

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_031841.3
• Gene: Cyp2c29 / 13095
• MGIID: 103238
• Length: 490
• Species: Mus musculus
• Alignment Length: 481
• Identity: 163/481 - (33%)
• Similarity: 249/481 - (51%)
• Gaps: 43/481 - (8%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMG----SEKHTRFMELAKQYGSL 87
            |:|||.|.....:|..|.|......||||||..||:||..|.:.    |:..|.|   :|.||.:
Mouse     3 LVVFLALTLSCLILLSLWRQSSGRGKLPPGPTPLPIIGNFLQIDVKNISQSFTNF---SKAYGPV 64

  Fly    88 FSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQ-TLNGYGIINSTGKLWKDQRRFLHD 149
            |:..|||:.||::..|:.::|..  |.|||.||...|..: .:.|:|::.|.|..||:.|||...
Mouse    65 FTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLM 129

  Fly   150 KLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSI 214
            .||..||     ||:.::.|:..|....:..|..:.|.|.|.:.::|.|..|||||::...||..
Mouse   130 TLRNLGM-----GKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDY 189

  Fly   215 DDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSI----STAKNKIAQNRAEMQRFYQDVIDD 275
            .|.:|......|.|.:::...    .::.....|||:    ..:.:||.:|...::.:..:.|.:
Mouse   190 KDKEFLILMDKINENVKILSS----PWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKE 250

  Fly   276 HKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQ-------LVQVIIDLFSAGMETI 333
            ||.|.|..|.||.:|:||.:.::.             ||.||       |...|.|||.||.||.
Mouse   251 HKESLDVTNPRDFIDYYLIKQKQV-------------NHIEQSEFSLENLASTINDLFGAGTETT 302

  Fly   334 KTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATT 398
            .|||.:..:.:|:.|....:||:|:|:||||||.|.::|..::|.|::.|.|..|...::|.:..
Mouse   303 STTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLP 367

  Fly   399 HSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGR 463
            |:.|.|::...|.||.|:.||..::||..|...:..||.|.|..|::..|..:|.:||:||..|:
Mouse   368 HAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKKSDYFMPFSTGK 432

  Fly   464 RMCLGDVLARMELFLFFASFMHCFDI 489
            |:|.|:.||||||||...:.:..|.:
Mouse   433 RICAGEGLARMELFLILTTILQNFKL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	139/419 (33%)
Cyp2c29	NP_031841.3	CYP2C-like	61..485	CDD:410758	140/420 (33%)