Protein Alignment Cyp18a1 and LOC100912642

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_008762180.2
• Gene: LOC100912642 / 100912642
• RGDID: 6486125
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 429
• Identity: 148/429 - (34%)
• Similarity: 233/429 - (54%)
• Gaps: 28/429 - (6%)

  Fly    97 TVVMSDYKMIRECFRR--EEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTY 158
            :|::|...:|:|.|..  |.|..||..|..:.: |..|:|.|:|:.||:||||....||.||:
  Rat     3 SVIISSLPLIKEAFSHLDENFINRPIFPLQKHIFNDNGLIFSSGQTWKEQRRFALMTLRNFGL-- 65

  Fly   159 MGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFN 223
               ||:.:::||..|.|..:..:...:|||.|....|:.||||:|||:....||...|.:|:...
  Rat    66 ---GKKSLEQRIQEEAHHLVEAIGEEEGQPFDPHFKINNAVSNIICSITFGERFEYHDSQFQELL 127

  Fly   224 FLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNR------AEMQRFYQDVIDDHKRSFDP 282
            .|:::.|.|    .|...|.....||.|  .|:...|::      .:::.:..|:|::|:..::|
  Rat   128 KLLDKAMYL----GTPMMIHLYNMFPWI--IKHLPGQHQTLLATWGKLKSYIADIIENHREDWNP 186

  Fly   283 NNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRN 347
            ...||.:|.:|.|:.|...:.|.:      .:||.|:...:|||.||.||..|||.|..::|...
  Rat   187 AEPRDFIDAFLNEMAKYPDKTTTS------FNEENLICSTLDLFLAGTETTSTTLRWAVLYMALY 245

  Fly   348 PKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTI 412
            |:...:||.|:|||:|:.:.|::.|...:|.|.:.:.|..|..:||||........|..|.|:.:
  Rat   246 PEVQEKVQAEIDQVIGQEKHPSLADRDSMPYTNAVVHEIQRMGNIVPLNVPREVAVDTTLAGFHL 310

  Fly   413 PAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELF 477
            |.||.|:..:.::||||..|..|:.|.|..|:: .|:.:|.:.|:||.:|:|.|||:.|||.|||
  Rat   311 PKGSVVMTNLTALHMDPKEWATPDVFNPEHFLE-NGQFKKRDSFLPFSMGKRACLGEQLARSELF 374

  Fly   478 LFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            :||.:.|..|....|..:.| |||..:|.||:|.|.::|
  Rat   375 IFFTALMQKFTFKPPTNEKL-SLKFRLGITISPVSHRIC 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	147/426 (35%)
LOC100912642	XP_008762180.2	CYP2J	1..411	CDD:410755	147/426 (35%)