Protein Alignment Cyp18a1 and cyp2a6.3

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_002939425.2
• Gene: cyp2a6.3 / 100497184
• XenbaseID: XB-GENE-5903984
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 498
• Identity: 156/498 - (31%)
• Similarity: 258/498 - (51%)
• Gaps: 48/498 - (9%)

  Fly    28 MVFLGL--LALVTLLQWLV----RNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR-FMELAKQYG 85
            |..||:  |.||....:||    |..|..| |||||..||::|.:|.:...|..: |::|..|||
 Frog     6 MAVLGIETLFLVCSFTFLVFLFSRRQRHAR-LPPGPTPLPLLGNVLQLDFSKQVKEFVKLGSQYG 69

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFL 147
            .:....||....:|::.|.:::|.|  ..|.|:.|....|::.: .|.|:..|.|:.|:..|||.
 Frog    70 PVSMVYLGPYPVLVLNGYDVVKEAFVDNGEVFSNRGKNAFIEMIFKGRGVAFSNGERWRQMRRFS 134

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRF 212
            ...||.|||     ||:::::|:..|....:.....:.|.|.:.:.::::||||||||::...||
 Frog   135 LSTLRDFGM-----GKRRVEERVQEEACALVEEFKKTKGTPFNSTYLMTLAVSNVICSVVFGERF 194

  Fly   213 SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCF-------PSISTAKNKIAQNRAEMQRFYQ 270
            ...:..|.....|:::..::...       |..|.|       ..:.....|.|:|...::.|..
 Frog   195 DYQNETFLSVLALLKDTFKIITS-------PWTQLFSFAPGLLKHLPGPHKKAAENLDRLKTFVT 252

  Fly   271 DVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHE---EQLVQVIIDLFSAGMET 332
            :.:..|:.:.:.|..||.:|.:|.::.:.|         |..|.|   |.|...:::||.||.||
 Frog   253 EFVASHEETLEENFPRDYIDCFLIKMRQEK---------DNVNTEFDYENLFVTLMNLFFAGTET 308

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLAT 397
            ...||.:..:.:|:.|...:::.:|:|.|:|.:|.|::||...:|.|::||.|..|.:.|||:..
 Frog   309 TSITLQYGMLILLKYPDIQKKIHEEIDSVIGFNRCPSMEDRPKMPYTDATIHEIQRFADIVPMGV 373

  Fly   398 THSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVG 462
            ..|..:|..|.||.||.|:.|.|::..:..||..::.||.|.|..|:|.:|.::|.:.||||.:|
 Frog   374 PRSTNKDTTLRGYDIPKGTTVFPMLTCILKDPRYFKDPESFNPCHFLDEKGCLKKTDAFIPFSIG 438

  Fly   463 RRMCLGDVLARMELFLFFASFMHCFDIAL---PEG---QPLPS 499
            :|:|||:.|||||:|||..|.:..|::..   |:.   .|:||
 Frog   439 KRVCLGEGLARMEIFLFLTSILQRFELKCHMDPKDIDISPVPS 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	144/466 (31%)
cyp2a6.3	XP_002939425.2	p450	48..492	CDD:365848	137/455 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm48967
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970