Protein Alignment Cyp18a1 and cyp1c1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001191176.1
• Gene: cyp1c1 / 100496802
• XenbaseID: XB-GENE-29077131
• Length: 524
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 165/519 - (31%)
• Similarity: 275/519 - (52%)
• Gaps: 31/519 - (5%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            |:..||.|:.|...| ||..|.:  |:.||||:..||:|..:.:|...|..|.:::::||::|..
 Frog    21 LVFSFLILICLEVCL-WLRNNGQ--RRSPPGPFPWPVVGNAMQLGQLPHLTFCKMSQKYGNVFQI 82

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNGYGIINSTG--KLWKDQRRFLHDKL 151
            |||:|..||::....|||..  ..:||.|||:....|.::|...|...|  .|||.|::..|..|
 Frog    83 RLGTQDIVVLNGDSTIREALVKHSKEFAGRPNFSSFQLISGGKSIAFGGYSTLWKAQKKIAHSTL 147

  Fly   152 RQFGMTYMGNGKQQ--MQKRIMTEVHEFIGHL--HASDGQPVDMSPVISVAVSNVICSLMMSTRF 212
            |.|...   |.|.|  .:|.::.|..:.|...  ..|:.:..|.:...:||.:||||:|....|:
 Frog   148 RAFSTV---NSKTQKLFEKHVVAEAQDLIDVFLRLTSEEEYFDPTRECTVAAANVICALCFGKRY 209

  Fly   213 SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPS-ISTAKNKIAQNRAEMQRFYQDVIDDH 276
            |.||.:|:......::..:..|....||.:|.:..||: :.:..........|...|.::.:..|
 Frog   210 SHDDEEFKALIGRNDKFGQTVGAGSLVDIMPWLLTFPNPVRSLYQSFKDLNWEFYGFVKEKVSHH 274

  Fly   277 KRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDG--KNHEEQLVQVIIDLFSAGMETIKTTLLW 339
            :::::|...||:.|.::..|:  .|||.:|.  ||  |::.|.:|.   |:..||.:|..|.|.|
 Frog   275 RQTYNPEIARDMSDAFISHID--NAEGIEAG--DGLSKDYVESIVN---DILGAGQDTTATALTW 332

  Fly   340 INVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRD 404
            |.:.:::.|...:::|:|:|.|||.:||||.:|...||..::.|.|::|.||.||:...||.|.|
 Frog   333 ILLLLIKYPDIQQKLQEEIDLVVGPNRLPTADDKVQLPYVQAFIYEALRFSSFVPVTIPHSTTSD 397

  Fly   405 VELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYF--IPFGVGRRMCL 467
            |.::|:.||..:.|.....||:.|.:.|:.|:.|.||||:|.||::.:...|  :.|.||:|.|:
 Frog   398 VVIDGFYIPKDTVVFVNQWSVNHDESKWKNPDVFDPSRFLDEEGQLDRDAAFGVMIFSVGKRRCI 462

  Fly   468 GDVLARMELFLFFASFMHCFDIALPEGQP--LPSLKGNVGATITPESFKVCLKRRPLGPTAADP 529
            ||.|:.:::||..|.|:|...:   .|.|  :|::....|.::.|..:.:.::.|....|..:|
 Frog   463 GDQLSMLQIFLCTAIFLHQCTL---HGNPKEIPTMDCISGLSLKPLPYGMSVRARVGRTTMKEP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	141/444 (32%)
cyp1c1	NP_001191176.1	CYP1B1-like	76..509	CDD:410768	142/445 (32%)