Protein Alignment Cyp18a1 and cyp2c8.1

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_002937251.3
• Gene: cyp2c8.1 / 100491837
• XenbaseID: XB-GENE-5831571
• Length: 558
• Species: Xenopus tropicalis
• Alignment Length: 481
• Identity: 152/481 - (31%)
• Similarity: 247/481 - (51%)
• Gaps: 36/481 - (7%)

  Fly    20 DGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQY 84
            |.|...||::.|.||    ||.|  |.|::...|||||:.||::|.:|...:..:..:.:|::||
 Frog    65 DMDVLTLLLILLSLL----LLFW--RRYKKRLDLPPGPFPLPLLGNILQGKAVLYESYRKLSEQY 123

  Fly    85 GSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRF 146
            |.:|:..|||...||:..|:::::..  ....|..|...|..:.| .||||:...|:.||..|||
 Frog   124 GPVFTVWLGSTPVVVLCGYEVLKDALIDHAHLFGARGSLPITERLTKGYGIVGVNGERWKQMRRF 188

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            ....||.|||     ||:.|::||..|....:..:..:.|:.:|...::..:|:|:|..::...|
 Frog   189 AVTTLRNFGM-----GKRSMEERIQEEALHLVQAIQQAGGERLDPLDLLERSVNNIINLVVFGRR 248

  Fly   212 FSIDDPKFRRF----NFLIEEGMRLFGEIHTVDYIPTMQCFPSIST----AKNKIAQNRAEMQRF 268
            :..:|.:..::    |.||.......|.|::        .||.|..    ...||.|:...:..|
 Frog   249 WDYEDKQCLKYLSITNSLIGLIRSPLGLIYS--------AFPRIMRYLPGPHQKIFQDSDVLTSF 305

  Fly   269 YQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETI 333
            :::.|..|..:.|.::.||.:|.:|.:..:.|      :|.:.:...:.||..|:||:.||.||.
 Frog   306 FREQIHSHWNTLDFDSPRDFIDCFLIKANEEK------DLNESEFCSDNLVYSILDLYVAGTETT 364

  Fly   334 KTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATT 398
            ..|:.:..:.|::.|....:||.|:|:.||..|||.:.|..::..|.:.|.|..|...:||:|..
 Frog   365 TNTMQFALLVMMKYPHIQVKVQMEIDKAVGSDRLPGVADRAHMHYTNAVIHEIQRFLDLVPMALP 429

  Fly   399 HSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGR 463
            |..|.|....|:.||.|:.|||::.|...||..|:.|||..|..|::.:|:......||||..|:
 Frog   430 HMVTEDTVFRGFNIPKGTTVIPILGSALWDPGHWKSPEELNPEHFLNEKGQFCNQAAFIPFSAGK 494

  Fly   464 RMCLGDVLARMELFLFFASFMHCFDI 489
            |:|.|:.|||||:|:||.:.:..|.|
 Frog   495 RICPGEGLARMEIFIFFTALLQKFTI 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	139/447 (31%)
cyp2c8.1	XP_002937251.3	CYP2	123..547	CDD:410652	129/417 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm48967
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970