Protein Alignment Cyp18a1 and cyp2a6.4

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_004917148.2
• Gene: cyp2a6.4 / 100486002
• XenbaseID: XB-GENE-22064357
• Length: 493
• Species: Xenopus tropicalis
• Alignment Length: 497
• Identity: 158/497 - (31%)
• Similarity: 256/497 - (51%)
• Gaps: 45/497 - (9%)

  Fly    27 LMVFLGLLA--LVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR-FMELAKQYGSLF 88
            |..||.:|.  ::||..|... |::: .|||||..||:||.|:.:...|... .|:|.:|||:::
 Frog     6 LGTFLLVLITFILTLSSWNTM-YKKV-NLPPGPTPLPLIGNLMNIKKGKMVNSLMKLWEQYGAVY 68

  Fly    89 STRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLN----GYGIINSTGKLWKDQRRFL 147
            :...|::..:|:..|..::|..  :.|:|..|..   :.||:    .||:..|.|:.|:..|.|.
 Frog    69 TLYFGTKRIIVLCGYDAVKEALVNQAEDFGARGK---ISTLDPVTQDYGLSFSNGERWRQMRHFT 130

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRF 212
            ...|:.|||     ||:.::::|..|....:..:..|...|||.|.:|..|||||.||:|...||
 Frog   131 LKTLKNFGM-----GKKSIEEKIQEEALCLVEEIRKSGETPVDPSKLIMDAVSNVFCSIMFGRRF 190

  Fly   213 SIDDPKFRRFNFLIEEGMRL----FGEIHTVDYIPTMQCF-PSISTAKNKIAQNRAEMQRFYQDV 272
            ..::.||......:.|..||    :|::.::  .|::..: |.....||.:::   |:..|..:.
 Frog   191 EYNEEKFSNLLTNVNEIFRLMSNTWGQLESI--FPSVMAYIPGPHKKKNTLSE---ELISFLHER 250

  Fly   273 IDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFS---AGMETIK 334
            :..::.:|||:..||.:|.||.:||:.|         ...|.|..:...::..||   .|.||..
 Frog   251 VKSNQETFDPSAPRDFIDEYLMKIEQEK---------KNPNSEFTMRNTLLTFFSIFLGGTETST 306

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            ||:....:.:::.|:...::..|:|.|:||:|:..|.|...:|..|:.|.|..|.|.|.||....
 Frog   307 TTIKHGLLLLIKYPEIQAKLHMEIDHVIGRNRIVNINDRNAMPYMEAVINEIQRFSDIAPLNAPR 371

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRR 464
            ..|:||:..||:||..:.:.||:.:||.||..:..|.||.||.|:|.:|:.||.|..:.|..|:|
 Frog   372 KVTKDVQFRGYSIPKDTEIYPLLCTVHRDPKYFSSPYEFNPSHFLDEQGRFRKSEAMMAFSAGKR 436

  Fly   465 MCLGDVLARMELFLFFASFMHCFDIALP----EGQPLPSLKG 502
            :|.|:.||||||||||.:.:..|.:..|    |....|.:.|
 Frog   437 ICPGESLARMELFLFFTTILQNFTLTSPTHFTEDDVAPKMAG 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	149/468 (32%)
cyp2a6.4	XP_004917148.2	CYP2	64..487	CDD:410652	136/437 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970