Protein Alignment Cyp18a1 and cyp2b6

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001096373.1
• Gene: cyp2b6 / 100124967
• XenbaseID: XB-GENE-5779150
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 498
• Identity: 176/498 - (35%)
• Similarity: 275/498 - (55%)
• Gaps: 25/498 - (5%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK-HTRFMELAKQYGSLFST 90
            :.:.|.:...|.||........:.:..||||..||:||.||.|..:| |..|||||::|||:||.
 Frog     4 ISILLSIAVCVFLLNLFYGGKGDSKMFPPGPKPLPLIGNLLIMNMKKPHLTFMELAEKYGSVFSV 68

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLN-GYGIINSTGKLWKDQRRFLHDKLR 152
            :||::..||:.....:::..  ..:||:.||..|..:.:: |||:|.|.|:.||..|||....||
 Frog    69 QLGTEKVVVLCGTDAVKDALINHADEFSERPKIPIFEDVSKGYGLIFSHGENWKVMRRFTLTTLR 133

  Fly   153 QFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDP 217
            .|||     ||:.:::||..|....:....:..|:|.:.:.:::.||:|:|.|:::..||...|.
 Frog   134 DFGM-----GKKTIEERICEESDCLVEAFKSYKGKPFENTLIMNAAVANIIVSILLGHRFDYQDT 193

  Fly   218 KFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSIS---TAKNK-IAQNRAEMQRFYQDVIDDHKR 278
            ...:...:|.|.:||.|....:.|    ..:||:.   ..|:| :|:|..::.:|.::....|:.
 Frog   194 ALLKLIKIINENVRLMGSPMVMLY----NTYPSVMQWLPGKHKTVAENTLKLFKFLEETFTKHRD 254

  Fly   279 SFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVF 343
            ..|.|:.|||||.:|  :::.:.:.:.::.|    |::.|..::.:||.|||||..|||.|..:.
 Frog   255 QLDVNDQRDLVDTFL--VKQQEEKPSSSKFF----HDQNLTLLVSNLFGAGMETTSTTLRWGLLL 313

  Fly   344 MLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELN 408
            |::.|...::||||:|:|:|... |..|..:.:|.|::.|.|..|.::|.|....|:.||||...
 Frog   314 MMKYPDIQKKVQDEIDKVIGSAE-PQTEHRKQMPYTDAVIHEIQRFANIAPSNLPHATTRDVTFR 377

  Fly   409 GYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLAR 473
            ||.||.|:.||||:.||..|.|.::|||||.|..|:|:||...|.|.|:||..|||.|.|:.||:
 Frog   378 GYFIPKGTQVIPLLTSVLQDKNYFKKPEEFYPEHFLDSEGHFMKNEAFLPFSAGRRSCAGETLAK 442

  Fly   474 MELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            |||||||...:..|....|.|..:....|. |.|.:|....:|
 Frog   443 MELFLFFTKLLQNFTFQPPPGVEVQLTSGE-GFTSSPLQHNIC 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	172/471 (37%)
cyp2b6	NP_001096373.1	p450	31..466	CDD:306555	167/450 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm48967
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050