Protein Alignment Cyp18a1 and cyp2f1l

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001421396.1
• Gene: cyp2f1l / 100124950
• XenbaseID: XB-GENE-5870895
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 503
• Identity: 173/503 - (34%)
• Similarity: 269/503 - (53%)
• Gaps: 27/503 - (5%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK-HTRFMELAKQYGSLFST 90
            :.:||.::..:.|:..:..........||||..||:||.|..:..:| :..||||.|:|||:|..
 Frog     7 ITLFLAIVICLFLIYLVYGGKGTPPNFPPGPKPLPLIGNLHIINLKKPYMTFMELGKKYGSVFRV 71

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRP--DTPFMQTLNGYGIINSTGKLWKDQRRFLHDKL 151
            :||::..||:..|..:::..  ..|||:.||  :| |.:..||:||..|.|:.||..|||....|
 Frog    72 QLGTEKVVVLCGYDAVKDALINHAEEFSDRPIIET-FHRRSNGHGITFSHGENWKVMRRFTIATL 135

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            |.|||     ||:.::.||..|.|..:....:..|:|.:.:.:::.||:|:|.|:::..||...|
 Frog   136 RDFGM-----GKRTIEDRINEECHSLVETFQSYKGEPFETNLIMNAAVANIIVSILLGHRFEYQD 195

  Fly   217 PKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSIST----AKNKIAQNRAEMQRFYQDVIDDHK 277
            |...:...|..|.:|:.|....:.|    ..:||:..    :.:.:.:|..:...|.::...:||
 Frog   196 PTLLKLIGLSNEMVRILGSPIVLLY----NAYPSVMKWLPGSHHNVIKNTQKSHTFIKETFTEHK 256

  Fly   278 RSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINV 342
            ...|.|:.||.:|.:|.   |...|..:..||   .|.|.||.::..||.|||||..|||.|..:
 Frog   257 AQLDINDQRDFIDAFLA---KQSEEKPNPGLF---FHNENLVSLVDGLFVAGMETTSTTLRWGLL 315

  Fly   343 FMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVEL 407
            .|::.|:..::||||:::|:|..: |..|..:.:|.|::.|.|..|.:.|:|....|:.|:||..
 Frog   316 LMMKYPEIQKKVQDEINKVIGSAQ-PQTEHRKQMPYTDAVINEIQRFADIIPANLPHATTKDVTF 379

  Fly   408 NGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLA 472
            .||.||.|:.|||::.||..|...:|:|.||.|..|:|::|...|.|.|:||..|:|.|.|:.||
 Frog   380 RGYFIPKGTQVIPMLTSVLRDKAYFERPYEFYPQHFLDSKGNFVKNEAFLPFSAGKRSCAGETLA 444

  Fly   473 RMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            :|||||||.:.:..|....|.||.| :|....|.|..|...|:|...|
 Frog   445 KMELFLFFTNLLQNFTFQPPPGQDL-NLTTTGGFTSVPVVHKICALSR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	151/437 (35%)
cyp2f1l	NP_001421396.1	cytochrome_P450	65..486	CDD:477761	152/438 (35%)