Protein Alignment Cyp18a1 and cyp2p8

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001076504.1
• Gene: cyp2p8 / 100034366
• ZFINID: ZDB-GENE-061030-1
• Length: 496
• Species: Danio rerio
• Alignment Length: 511
• Identity: 179/511 - (35%)
• Similarity: 271/511 - (53%)
• Gaps: 54/511 - (10%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK-HTRFMELAKQYGSLFST 90
            :::|   |.:..||...::| :..:..|||||.||:||.|..:.:.| |.:|.:.|::||::||.
Zfish    15 ILIF---LCVFLLLGDYIKN-KAPKNFPPGPWSLPIIGDLHHIDNSKIHLQFTKFAERYGNIFSF 75

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTP-FMQTLNGYGIINSTGKLWKDQRRFLHDKLR 152
            ||.....||::.|.:::|.:  :.:....||..| |.:.:...|:|.|:|..||.||||....||
Zfish    76 RLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIVGDKGLILSSGYKWKHQRRFALSTLR 140

  Fly   153 QFGMTYMGNGKQQMQKRIMTE---VHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSI 214
            .||:     ||:.::..|..|   ::|.|.:   ..|:|.|...:::.|||||||.|:...||..
Zfish   141 NFGL-----GKKSLEPSINVECGFLNEAISN---EQGRPFDPRLLLNNAVSNVICVLVFGNRFDY 197

  Fly   215 DDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFP-----------SISTAKNKIAQNRAEMQRF 268
            .|..|:.....|.|.:.|.|.|....|    ..||           :|.|...|:..       |
Zfish   198 SDHHFQTLLKNISEAVYLEGSICNQLY----NMFPWLMERLPGPHKTIITLWRKVTD-------F 251

  Fly   269 YQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAK---AEGTDAELFDGKNHEEQLVQVIIDLFSAGM 330
            .::.:::|:..:||:|.||.:|.:|.|:||.|   |.|.|.         |.|....:|||.||.
Zfish   252 VREKVNEHRVDYDPSNPRDYIDCFLTEMEKLKDDTAAGFDV---------ENLCICSLDLFVAGT 307

  Fly   331 ETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPL 395
            ||..|||.|..::|::.|:...:||:|:|.|||..|.|::.|...:|.|.:.|.|..|..:|.|:
Zfish   308 ETTSTTLYWGLLYMIKYPEIQAKVQEEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIAPI 372

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFG 460
            ....|.:.|.::..|:||.|:.|...:.||..|.:.||.|..|.|..|:|.|||.|:.:.|:||.
Zfish   373 NLARSTSEDTQIGNYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS 437

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            :|:|:|||:.||||||||||:|.:..|..:.|.|.. |||...:|.|..|:.||:|
Zfish   438 LGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVE-PSLDYKMGGTHCPKPFKLC 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	157/449 (35%)
cyp2p8	NP_001076504.1	CYP2	69..491	CDD:410652	158/450 (35%)