DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP89A5

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_176675.1	Gene:	CYP89A5 / 842803	AraportID:	AT1G64950	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	143/570 - (25%)
Similarity:	240/570 - (42%)	Gaps:	101/570 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLVPGALVL-VILYLCERQCNDLMGAP-PPGPWGLPFLGYLPFL--DARAPHKSLQKLAKRYGGI 83
            ||:.|:|.| ::|.|...:..|....| ||.|...||:|.:.:|  .....:..|:.:..|.|.|
plant     5 LLILGSLFLSLLLNLLFFRLRDSSSLPLPPDPNYFPFIGTIQWLRQGLGGLNNYLRSVHHRLGPI 69

  Fly    84 FELKMGRVPTVVLSDAALVRDFFRRDVMTG--------RAPLYL-----THGIMGGFGIICAQED 135
            ..|::...|::.::|.:|.....   |:.|        .||:..     .|.|..     |....
plant    70 ITLRITSRPSIFVADRSLAHQAL---VLNGAVFADRPPAAPISKIISSNQHNISS-----CLYGA 126

  Fly   136 IWRHARRE-TIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHH 199
            .||..||. |.:.|       .|..:|:....|  |.|.|.  |||...|......:..:..||:
plant   127 TWRLLRRNLTSEIL-------HPSRVRSYSHAR--RWVLEI--LFDRFGKNRGEEPIVVVDHLHY 180

  Fly   200 SLGNIINDLVFGITYKRDDPDWL---YLQRLQEEGVKLIGVS--GVVNFLPWLRHLPANVRNIRF 259
            ::..::..:.||  .|.|:....   |:||.|     |:|.|  .::|..|            :|
plant   181 AMFALLVLMCFG--DKLDEKQIKQVEYVQRRQ-----LLGFSRFNILNLWP------------KF 226

  Fly   260 LLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADE 324
                   |..|..:..|...|..:|:..|...|   .|.:|::.:|:..:|         ||.:|
plant   227 -------TKLILRKRWEEFFQMRREQHDVLLPL---IRARRKIVEERKNRS---------SEEEE 272

  Fly   325 DDEESDEE--DTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLA 387
            |::|..:.  ||     :||  |.:.|...:|. :|::..|.::....|.||:...|:|.:..|.
plant   273 DNKEYVQSYVDT-----LLE--LELPDEKRKLN-EDEIVSLCSEFLNGGTDTTATALQWIMANLV 329

  Fly   388 REQRCQRRLHELLLPL----GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGD 448
            :....|:||:|.:..:    ......|:.:.:.||.|.:.|.:|........:||...|:.|:|.
plant   330 KNPDIQKRLYEEIKSVVGEEANEVEEEDAQKMPYLEAVVMEGLRRHPPGHFVLPHSVTEDTVLGG 394

  Fly   449 YFI-KGGSM-IVCSEWAIHMDPVAFPEPEEFRPERFL--TADGAYQAPPQFIPFSSGYRMCPGEE 509
            |.: |.|:: .:.:|  |..||..:.||..|:||||:  ..|.......:.:||.:|.|:|||..
plant   395 YKVPKNGTINFMVAE--IGRDPKVWEEPMAFKPERFMEEAVDITGSRGIKMMPFGAGRRICPGIG 457

  Fly   510 MARMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
            :|.:.|..:...::|.|..:...|.|||:..:...|:. ..|.|:...:|
plant   458 LAMLHLEYYVANMVREFDWKEVQGHEVDLTEKLEFTVV-MKHPLKALAVP 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	133/536 (25%)
CYP89A5	NP_176675.1	CYP77_89	65..501	CDD:410698	124/503 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000