DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phm and CYP78A8

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_171627.2	Gene:	CYP78A8 / 839233	AraportID:	AT1G01190	Length:	540	Species:	Arabidopsis thaliana

Alignment Length:	510	Identity:	120/510 - (23%)
Similarity:	195/510 - (38%)	Gaps:	109/510 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGG--IFELKMGRVPTVVLSDAALVRDFFRRDVMT 112
            |||.|.|.:|.:....:...|:.:..:|:....  :....:|....||....|:.::.....|..
plant    80 PGPRGFPLVGSMSLRSSHVAHQRIASVAEMSNAKRLMAFSLGDTKVVVTCHPAVAKEILNSSVFA 144

  Fly   113 GRAPLYLTHGIM----GGFGIICAQEDIWRHARRETIDWLKALGMTR--RPGELR-ARLERRIAR 170
            .|......:|:|    .||   ......||..||        ||...  .|.::: :..:||:.
plant   145 DRPVDETAYGLMFNRAMGF---APNGTYWRTLRR--------LGSNHLFNPKQIKQSEDQRRVI- 197

  Fly   171 GVDECVRLFDTEAKKSCA-SEVNPLPALHHSLGNIINDLVFGITYKRDDPDWL---YLQRLQEEG 231
             ..:.|..|....|.:|| .::....:|.:.:|     ||||..|:.:..:.|   .|:.|.|||
plant   198 -ATQMVNAFARNPKSACAVRDLLKTASLCNMMG-----LVFGREYELESNNNLESECLKGLVEEG 256

  Fly   232 VKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQK 296
            ..|:|.....:.||||..|  :.:.|||                 .|.|.:.:...:...:..:
plant   257 YDLLGTLNWTDHLPWLAGL--DFQQIRF-----------------RCSQLVPKVNLLLSRIIHE- 301

  Fly   297 RLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLR 361
              ||......|........|::.||:|                    .:||
plant   302 --QRAATGNFLDMLLSLQGSEKLSESD--------------------MVAV-------------- 330

  Fly   362 HLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH-ELLLPLGPSPTLEE--LEPLAYLRACIS 423
              |.::...|.||....:.|.|..:....:.|..:| ||...:|.|.|::|  |..|.||.|.|.
plant   331 --LWEMIFRGTDTVAVLVEWVLARIVMHPKVQLTVHDELDRVVGRSRTVDESDLPSLTYLTAMIK 393

  Fly   424 ETMRIRSVVP------LGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERF 482
            |.:|:....|      |.|     .:..|..|.:..|:..:.:.|||..||..:.:|.||:||||
plant   394 EVLRLHPPGPLLSWARLSI-----TDTSVDGYHVPAGTTAMVNMWAIARDPHVWEDPLEFKPERF 453

  Fly   483 LTADG-----AYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPS 532
            :..:|     .:.:..:..||.||.|:|||:.:....::.:...:|..|.. |||
plant   454 VAKEGEAEFSVFGSDLRLAPFGSGKRVCPGKNLGLTTVSFWVATLLHEFEW-LPS 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	120/510 (24%)
CYP78A8	NP_171627.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000