DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP78A5

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_172827.1	Gene:	CYP78A5 / 837932	AraportID:	AT1G13710	Length:	517	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	122/574 - (21%)
Similarity:	213/574 - (37%)	Gaps:	120/574 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRY- 80
            :.:::.||.||.|.    :.........:..|.|.       |.|.......||:.|..||||:
plant    28 IATVAFLLSPGGLA----WAWTGSSKSRVSIPGPS-------GSLSVFSGSNPHRVLAALAKRFK 81

  Fly    81 -GGIFELKMGRVPTVVLSDAALVRDFFRRDVMTGR-----APLYLTHGIMGGFGIICAQEDIWRH 139
             ..:....:|....|:.|:....::.........|     |...|.|..||    .....:.||:
plant    82 ASPLMAFSVGFSRFVISSEPETAKEILSSSAFADRPVKESAYELLFHRAMG----FAPYGEYWRN 142

  Fly   140 ARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHH-SLGN 203
            .||.:...|.:      |..:.:....|:..|:....::.......:| .||.....:|. ||.|
plant   143 LRRISSTHLFS------PRRIASFEGVRVGIGMKMVKKIKSLVTSDAC-GEVEVKKIVHFGSLNN 200

  Fly   204 IINDLVFGITYKRDDPD--WLYLQRLQEEGVKLIGV---SGVVNFLPWLRHLPANVRNIRFLLEG 263
            ::. .|||.:|..|:.:  ..:|:||..||.:|:|:   |....||.|            |..:|
plant   201 VMT-TVFGESYDFDEVNGKGCFLERLVSEGYELLGIFNWSDHFWFLRW------------FDFQG 252

  Fly   264 KAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEE 328
            ..|          .|...:.|.......:         :||.::::....           :.||
plant   253 VRK----------RCRALVSEVNTFVGGI---------IEKHKMKKGNNL-----------NGEE 287

  Fly   329 SDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQ 393
            :|..|.          |.....|.:| .|..:..:|.::...|.||....:.|.|..:...|..|
plant   288 NDFVDV----------LLGLQKDEKL-SDSDMIAVLWEMIFRGTDTVAILVEWVLARMVLHQDIQ 341

  Fly   394 RRLHELLLPLGPSPTLEELEPLA--------YLRACISETMRIRSVVP------LGIPHGCKENF 444
            .:|:..:    .|.|...:..|:        ||:|.:.||:|:....|      |.|     .:.
plant   342 DKLYREI----ASATSNNIRSLSDSDIPKLPYLQAIVKETLRLHPPGPLLSWARLAI-----HDV 397

  Fly   445 VVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP-QFIPFSSGYRMCPGE 508
            .||...:..|::.:.:.|:|..:...:.:||.|.||||::.|.:..... :..||.||.|:|||:
plant   398 HVGPNLVPAGTIAMVNMWSITHNAKIWTDPEAFMPERFISEDVSIMGSDLRLAPFGSGRRVCPGK 462

  Fly   509 EMARMILTLFTGRILRRFH-------LELPSGTEVDMAGESGITLTPTPHMLRF 555
            .|....:.|:.|::::.|.       :||....::.|..::.:.....|..:.|
plant   463 AMGLATVHLWIGQLIQNFEWVKGSCDVELAEVLKLSMEMKNPLKCKAVPRNVGF 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	115/540 (21%)
CYP78A5	NP_172827.1	CYP78	81..505	CDD:410699	104/497 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050