Protein Alignment phm and Cyp2c23

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_114027.2
• Gene: Cyp2c23 / 83790
• RGDID: 620370
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 146/531 - (27%)
• Similarity: 233/531 - (43%)
• Gaps: 95/531 - (17%)

  Fly    46 GAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RR 108
            |..||||..||.:|.|..|:.:....||.||||.||.::.|..|..|||||....:|::..  :.
  Rat    31 GRLPPGPTPLPIIGNLLQLNLKDIPASLSKLAKEYGPVYTLYFGTSPTVVLHGYDVVKEALLQQG 95

  Fly   109 DVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVD 173
            |...||.||.:......|:|:|.:..:.|:..||.::..|:..||.:|      .||.|    |.
  Rat    96 DEFLGRGPLPIIEDTHKGYGLIFSNGERWKVMRRFSLMTLRNFGMGKR------SLEER----VQ 150

  Fly   174 ECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVS 238
            |..|....|.:|:.|...:|...|..:..|:|..::|...::.::..:|.|..|..:..:.:...
  Rat   151 EEARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYNNKTFLNLMDLLNKNFQQVNSV 215

  Fly   239 GVVNFLPW---LRHLPA----------NVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFK 290
            ....:..|   :::||.          :|:|  |:|| |.|.|
  Rat   216 WCQMYNLWPTIIKYLPGKHIEFAKRIDDVKN--FILE-KVKEH---------------------- 255

  Fly   291 ELQEQKRLQRQLEKEQLRQSKEADPSQEQSEAD---EDDEESDEEDTYEPECILEHFLAVRDTDS 352
                               .|..||:..:...|   ...||  |:|..:.|..||: |||
  Rat   256 -------------------QKSLDPANPRDYIDCFLSKIEE--EKDNLKSEFHLEN-LAV----- 293

  Fly   353 QLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELL---LPLGPSPTLEELEP 414
               |.       ::||.||.:|:..|||:.||.|.:....|.::||.|   :.....|::::...
  Rat   294 ---CG-------SNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRHQPPSMKDKMK 348

  Fly   415 LAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRP 479
            |.|..|.:.|..|..:::|..:||...::....||.|..|:.::....::.:|...|..||:|.|
  Rat   349 LPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDP 413

  Fly   480 ERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLE-LPSGTEVDMAG-ES 542
            ..||..:|.::....|:|||.|.|.|.||.:|||.|.||...:|::|.|: |....::|:.. .:
  Rat   414 GHFLDKNGCFKKTDYFVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLDIKPITT 478

  Fly   543 GITLTPTPHML 553
            ||...|.|:.|
  Rat   479 GIINLPPPYKL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	145/528 (27%)
Cyp2c23	NP_114027.2	p450	34..491	CDD:278495	145/528 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000