DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP89A3

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_200940.1	Gene:	CYP89A3 / 836253	AraportID:	AT5G61320	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	124/545 - (22%)
Similarity:	211/545 - (38%)	Gaps:	132/545 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ILYLCERQCNDLMGAPP-------PGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKMGR 90
            :|||..|:.|:.:..||       |||:.....|:..|      :..|:.:..|.|.|..|::..
plant    17 LLYLFFRRTNNNLPLPPNPNFFPMPGPFQWLRQGFDDF------YSYLRSIHHRLGPIISLRIFS 75

  Fly    91 VPTVVLSDAALVRD--FFRRDVMTGRAPLYLTHGIM---------GGFGIICAQEDIWRHARRE- 143
            ||.:.:||.:|...  .....|.:.|.|...|..|:         |.:|.      .||..||.
plant    76 VPAIFVSDRSLAHKALVLNGAVFSDRPPALPTGKIITSNQHTISSGSYGA------TWRLLRRNL 134

  Fly   144 TIDWLKALGMTRRPGELRARLERRIARGVDE--CVRLFDTEAKKSCASEVNPLPALHH---SLGN 203
            |.:.|       .|..:::....|  |.|.|  |.|:      ::...|..|:..:.|   ::.:
plant   135 TSEIL-------HPSRVKSYSNAR--RSVLENLCSRI------RNHGEEAKPIVVVDHLRYAMFS 184

  Fly   204 IINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLP--WLRHLPA-NVRNI-----RFL 260
            ::..:.||             .:|.||.:|      .|.|:.  .|..||. |:.|:     :..
plant   185 LLVLMCFG-------------DKLDEEQIK------QVEFVQRRELITLPRFNILNVFPSFTKLF 230

  Fly   261 LEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADE- 324
            |..:.:....:.|          |.:.|...|...:|       :.:.:||::.....||..|.
plant   231 LRKRWEEFLTFRR----------EHKNVLLPLIRSRR-------KIMIESKDSGKEYIQSYVDTL 278

  Fly   325 -DDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAR 388
             |.|..||:....                    :|::..|.::...||.||:..||:|.:..|..
plant   279 LDLELPDEKRKLN--------------------EDEIVSLCSEFLNAGTDTTATTLQWIMANLVI 323

  Fly   389 EQRCQRRLHELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKG 453
            .:..::.:.|           ||::.:.||:|.:.|.:|:.....|.:||...|:..:|.|.:..
plant   324 GEEEEKEIEE-----------EEMKKMPYLKAVVLEGLRLHPPGHLLLPHRVSEDTELGGYRVPK 377

  Fly   454 GSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP----QFIPFSSGYRMCPGEEMARMI 514
            ......:...|..||..:.||.||:||||:..|.......    :.:||.:|.|:|||...|.:.
plant   378 KGTFNINVAMIGRDPTVWEEPMEFKPERFIGEDKEVDVTGSRGIKMMPFGAGRRICPGIGSAMLH 442

  Fly   515 LTLFTGRILRRFHLELPSGTEVDMA 539
            |..|...:::.|..:...|.|||::
plant   443 LEYFVVNLVKEFEWKEVEGYEVDLS 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	118/529 (22%)
CYP89A3	NP_200940.1	PLN00168	42..488	CDD:215086	116/520 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000