DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP71B10

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_200536.3	Gene:	CYP71B10 / 835831	AraportID:	AT5G57260	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	137/558 - (24%)
Similarity:	236/558 - (42%)	Gaps:	110/558 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            :|::|:...|::.:.:...|....     ||.|.|||.:|.|..| ...||:||.||:|:||.:.
plant     7 VSLILLISILLVAVKHSKRRWVRQ-----PPSPPGLPIIGNLHQL-GELPHQSLCKLSKKYGPVM 65

  Fly    85 ELKMGRVPTVVLSDAALVRDFFR--------RDVMTGRAPLYLTHGIMGGFGIICAQ-EDIWRHA 140
            .||:||||||::|.....:...:        |..:.|...|...:     ..|..:: :|.|:..
plant    66 LLKLGRVPTVIVSTPETAKQVLKDYDLHCCSRPSLEGTRKLSYNY-----LDIAFSRFDDYWKEL 125

  Fly   141 RRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLG-NI 204
            |:..::   .|...:|...::...|.       |..:|.|:.|:.:....:..|.....||. |:
plant   126 RKLCVE---ELFCNKRINSIQPIKEA-------EMEKLIDSIAESASQKTLVNLSDTFLSLNVNV 180

  Fly   205 INDLVFGITYK----RDDPDWLYLQRLQEEGVKLIGVSGVVNFLP-------WLRHLPA-NVRNI 257
            |...|||:.::    .:|.    .|.|..|.::::|.....:|.|       |...|.| ..|::
plant   181 ICKAVFGVNFQGTVLNNDK----FQDLVHEALEMLGSFSASDFFPYVGWIVDWFTGLHARRERSV 241

  Fly   258 RFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEA 322
            |.|       .|.|:::::...|:.:|:.:     .:...|..:||||
plant   242 RDL-------DAFYEQMIDLHLQKNREESE-----DDFVDLLLRLEKE----------------- 277

  Fly   323 DEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLA 387
                           |.:|.:....|         :.::.:|.::...|::||..|:.|.:..|.
plant   278 ---------------EAVLGYGKLTR---------NHIKAILMNILLGGINTSAITMTWAMAELI 318

  Fly   388 REQRCQRRLH-ELLLPLGPSP-----TLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVV 446
            |..|..:::. |:...:|.:.     :|:|:..|:||...|.||.|:..|.||.:|......|.:
plant   319 RNPRVMKKVQSEIRAQIGKNNKTRIISLDEINHLSYLNMVIKETCRLHPVAPLLVPREVISEFKI 383

  Fly   447 GDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP-QFIPFSSGYRMCPGEEM 510
            ..|.|:..:.:..:.|||..||..:.:||||.||||:..|...:... :.:||.||.|:||...|
plant   384 NGYTIQPKTRLHVNVWAIGRDPEIWKDPEEFLPERFMDCDIDVKGQDYELLPFGSGRRICPAVYM 448

  Fly   511 ARMILTLFTGRILRRFHLELPSGTEVD---MAGESGIT 545
            ....:......:|..|..:||.|..|:   |...||:|
plant   449 GITTVEFGLANLLYHFDWKLPEGVAVEDIYMDEASGLT 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	133/529 (25%)
CYP71B10	NP_200536.3	CYP71-like	60..493	CDD:410695	117/499 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050