DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP705A5

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_199610.1	Gene:	CYP705A5 / 834850	AraportID:	AT5G47990	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	128/563 - (22%)
Similarity:	225/563 - (39%)	Gaps:	103/563 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VLVILYLCERQCNDLM----------GAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            :.::|.|..|...||.          .|.||.|..||.:|:|..:.....|:|.:.::.:||.:.
plant    14 IFLLLCLFSRLSYDLFFRKTKDSRAGCALPPSPPSLPIIGHLHLILFVPIHQSFKNISSKYGPLL 78

  Fly    85 ELKMGRVPTVVLSDAALVRDFFR-RDV-MTGRAPLYLTHG-IMGGFGII-CAQEDIWRHARRETI 145
            .|:....|.|::|.|:...:.|: :|| ::.|.|..:... |:|....| ....|..:..::..:
plant    79 HLRFFNFPIVLVSSASTAYEIFKAQDVNVSSRPPPPIEESLILGSSSFINTPYGDYSKFMKKFMV 143

  Fly   146 DWLKALGMTRRPGELRA-RLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLV 209
            ..|......:|...:|| .|||.....:|:.::....|.:.......|          |.|..::
plant   144 QKLLGPQALQRSRNIRADELERFYKTLLDKAMKKQTVEIRNEAMKLTN----------NTICKMI 198

  Fly   210 FGITYKRDDPDWLYLQRLQEEGVKLIGVSGVV---------NFLPWLRHLPANVRNIRFLLEGKA 265
            .|             :...||..:...|.|:|         :||..:.|.|.....|....:...
plant   199 MG-------------RSCSEENGEAETVRGLVTESIFLTKKHFLGAMFHKPLKKLGISLFAKELM 250

  Fly   266 KTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESD 330
            .....:|.::|          |:..| .|:|..:.....:.|....||              ..|
plant   251 NVSNRFDELLE----------KILVE-HEEKLQEHHQTSDMLDMLLEA--------------YGD 290

  Fly   331 EEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQR-CQR 394
            |...|:                  ...||::.|..|||.||.:.|..|::|.:..:.:..: |:|
plant   291 ENAEYK------------------ITRDQIKSLFVDLFSAGTEASANTIQWTMAEIIKNPKICER 337

  Fly   395 RLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMI 457
            ...|:...:|.:..::|  |..|.||:|.:.|.:|:....|  :....||...:..::|...:.:
plant   338 LREEIDSVVGKTRLVQETDLPNLPYLQAIVKEGLRLHPPGP--VVRTFKETCEIKGFYIPEKTRL 400

  Fly   458 VCSEWAIHMDPVAFPEPEEFRPERFLTA------DGAYQAPPQFIPFSSGYRMCPGEEMARMILT 516
            ..:.:||..||..:.:||||:|||||.:      |...:...::|||.||.|.|||..:|..::.
plant   401 FVNVYAIMRDPDFWEDPEEFKPERFLASSRLGEEDEKREDMLKYIPFGSGRRACPGSHLAYTVVG 465

  Fly   517 LFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
            ...|.:::.|.. :..|.:::|.....:||| ..|.|:.|.:|
plant   466 SVIGMMVQHFDW-IIKGEKINMKEGGTMTLT-MAHPLKCTPVP 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	120/528 (23%)
CYP705A5	NP_199610.1	CYP93	75..504	CDD:410748	110/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050