DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP706A3

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_199275.1	Gene:	CYP706A3 / 834490	AraportID:	AT5G44620	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	141/558 - (25%)
Similarity:	238/558 - (42%)	Gaps:	117/558 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GALVLVILYLC-----ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            |..|:||..||     ..:|.......||||||||.:|.||||.... |...|.|||::|.||:|
plant    20 GLTVIVISTLCWCLWLYAKCKRRSPPLPPGPWGLPIIGNLPFLQPEL-HTYFQGLAKKHGPIFKL 83

  Fly    87 KMGRVPTVVLSDAALVRDFFR-RDVMTGRAPLYLTHGI--------MGGFGIICA-QEDIWRHAR 141
            .:|...|:|::.:.:.::..: .|:      ::..|.:        .||..||.: ....||..|
plant    84 WLGAKLTIVVTSSEVAQEILKTNDI------IFANHDVPAVGPVNTYGGTEIIWSPYGPKWRMLR 142

  Fly   142 RETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIIN 206
            :..::.:....|.....:||.|..|:..|.:.:..|:         .|.||....:...:.|::.
plant   143 KLCVNRILRNAMLDSSTDLRRRETRQTVRYLADQARV---------GSPVNLGEQIFLMMLNVVT 198

  Fly   207 DLVFGITYKRDDPDWL---YLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAK-- 266
            .:::|.|.|.::.:.:   :|:.::|.. .|:.|..:.:|.|.|.         ||.|:|.||
plant   199 QMLWGTTVKEEEREVVGAEFLEVIREMN-DLLLVPNISDFFPVLS---------RFDLQGLAKRM 253

  Fly   267 ------THAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADED 325
                  ...::|||:   .|||                                      ..|.|
plant   254 RRPAQRMDQMFDRII---NQRL--------------------------------------GMDRD 277

  Fly   326 DEESDEEDTYEPECILEHFLAVRDTDSQ---LYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLA 387
            ..:....|      .|:..|.|:|.:::   |..:| ::.:|.|:...|.||||..:.:.:..|.
plant   278 SSDGRAVD------FLDVLLKVKDEEAEKTKLTMND-VKAVLMDMVLGGTDTSLHVIEFAMAELL 335

  Fly   388 RE----QRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVV 446
            ..    :|.|:.:.::   :|....:||  :..|.|:.|.:.||:|:.:|.||.:|....:..||
plant   336 HNPDIMKRAQQEVDKV---VGKEKVVEESHISKLPYILAIMKETLRLHTVAPLLVPRRPSQTTVV 397

  Fly   447 GDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP---QFIPFSSGYRMCPGE 508
            |.:.|...|.|..:.||||.:|..:..|.:|.|:|||  |.:|....   .::||.||.|:|.|.
plant   398 GGFTIPKDSKIFINAWAIHRNPNVWENPLKFDPDRFL--DMSYDFKGNDFNYLPFGSGRRICVGM 460

  Fly   509 EMARMILTLFTGRILRRFHLELPSGTEVDMAGESGITL 546
            .|...::.......|..|..::|.|..|::..:.||.|
plant   461 AMGERVVLYNLATFLHSFDWKIPQGERVEVEEKFGIVL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	134/531 (25%)
CYP706A3	NP_199275.1	p450	21..518	CDD:299894	140/557 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050