DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP78A7

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_196559.1	Gene:	CYP78A7 / 830858	AraportID:	AT5G09970	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	626	Identity:	144/626 - (23%)
Similarity:	225/626 - (35%)	Gaps:	169/626 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 WMPSV------QSLSILLVPGALVLVILYLC--------------ERQCNDLMGAPPPGPWGLPF 57
            ||.::      |:|..:...|.|.|.:::|.              :...|.|.....|||.|:|.
plant    14 WMIALPAGFGSQNLHDVSTLGYLFLAVVFLSIVTWALAGGGGVAWKNGRNRLGRVAIPGPRGIPV 78

  Fly    58 LGYLPFLDARAPHKSLQKLA--KRYGGIFELKMGRVPTVVLSDAALVRD------FFRRDVMTGR 114
            .|.|..|.....|::|..:|  :....|....:|..|.:|.|:..:.|:      |..|.|....
plant    79 FGSLFTLSRGLAHRTLAAMAWSRANTEIMAFSLGSTPVIVASEPNIAREILMSPHFADRPVKQSA 143

  Fly   115 APLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLF 179
            ..|..:..|  ||   ......||              |.||.........|||.  ..|..|..
plant   144 KSLMFSRAI--GF---APNGTYWR--------------MLRRIASTHLFAPRRIL--AHEAGRQL 187

  Fly   180 D-TEAKKSCASEVN-----------PLPALHHSLGNIINDLVFGITY----KRDDPDWLYLQRLQ 228
            | .|..|:.:.|.|           .|.||::.:|:     |||..|    :::|.|  .|..:.
plant   188 DCAEMVKAVSVEQNGAGSVVLRKHLQLAALNNIMGS-----VFGRRYDPLAQKEDLD--ELTSMV 245

  Fly   229 EEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYD--RIVEACGQRLKEKQKVFKE 291
            .||.:|:|.....::||||.:                    .||  |:.:.|...:...:.:.|:
plant   246 REGFELLGAFNWSDYLPWLGY--------------------FYDSIRLNQRCSDLVPRIRTLVKK 290

  Fly   292 LQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYC 356
            :.::.|:....:|..:                     .|..|.          |...|.|.:|..
plant   291 IIDEHRVSNSEKKRDI---------------------GDFVDV----------LLSLDGDEKLQE 324

  Fly   357 DDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH-ELLLPLGPSPTLE----ELEPLA 416
            ||.:. :|.::...|.||:.....|.:..|......|.:|. |:|..:|.....:    :|..|.
plant   325 DDMIA-VLWEMIFRGTDTTALLTEWTMAELVLNPNVQTKLRDEILTAVGDGADGDVADADLAKLP 388

  Fly   417 YLRACISETMRIRSVVPL-----------GIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVA 470
            ||.|.:.||:|:....||           .:.:|         ..|..|:..:.:.|||..|...
plant   389 YLNAVVKETLRLHPPGPLLSWARLSTSDVQLSNG---------MVIPKGTTAMVNMWAITHDQTV 444

  Fly   471 FPEPEEFRPERFL-TADGAYQAPP-QFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSG 533
            :.:|.:|.||||. .||...:... :..||.:|.|:|||:.|....:|.:...::|||.......
plant   445 WSDPLKFDPERFTGNADMDIRGGDLRLAPFGAGRRVCPGKNMGLATVTRWVAELVRRFEWGQDQT 509

  Fly   534 TEVDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD 574
            ..||: ||             ..|| :.||.| |..|||.:
plant   510 EPVDL-GE-------------VLKL-SCEMEH-PLRAVVTE 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	125/549 (23%)
CYP78A7	NP_196559.1	CYP78	103..528	CDD:410699	119/529 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000