DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP93D1

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_196307.1	Gene:	CYP93D1 / 830580	AraportID:	AT5G06900	Length:	507	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	126/571 - (22%)
Similarity:	231/571 - (40%)	Gaps:	123/571 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAK 78
            |..:|..|::::....:.|::.....:..|.:.. ||.|..||.:|::..|...| |::|.||:.
plant     1 MVDLQYFSVIILVCLGITVLIQAITNRLRDRLPL-PPSPTALPIIGHIHLLGPIA-HQALHKLSI 63

  Fly    79 RYGGIFELKMGRVPTVVLSDAALVRD--------FFRRDVMTGRAPLYLTHGIMGGFGIICAQED 135
            |||.:..|.:|.:|.:::|.|.:..:        |..|..|....  |||:|
plant    64 RYGPLMYLFIGSIPNLIVSSAEMANEILKSNELNFLNRPTMQNVD--YLTYG------------- 113

  Fly   136 IWRHARRETIDWLKALGMTRRPGELRARLERRI-------ARGVDECVRLFDTEAKK-------- 185
                    :.|:..|      |..|..:..:||       :|.:|..|.:...|.||
plant   114 --------SADFFSA------PYGLHWKFMKRICMVELFSSRALDSFVSVRSEELKKLLIRVLKK 164

  Fly   186 -SCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRH 249
             .....||....|.....|||..::|              :::|.:.
plant   165 AEAEESVNLGEQLKELTSNIITRMMF--------------RKMQSDS------------------ 197

  Fly   250 LPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQE---QKRLQRQLEKEQLRQSK 311
                        :|..|:..:...:||     |.|....|...:.   .|||..|..|::|:.::
plant   198 ------------DGGEKSEEVIKMVVE-----LNELAGFFNVSETFWFLKRLDLQGLKKRLKNAR 245

  Fly   312 EADPSQEQSEADEDDEESDEEDTYEPECILEHFLAV-RDTDSQL-YCDDQLRHLLADLFGAGVDT 374
              |......|...::.||.:::......:|:..|.: .|.:::: ...:.::..:.:::|.|.||
plant   246 --DKYDVIIERIMEEHESSKKNATGERNMLDVLLDIYEDKNAEMKLTRENIKAFIMNIYGGGTDT 308

  Fly   375 SLATLRWFLLYLARE----QRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSVVP 433
            |..|:.|.|..|...    ::.|:.:.::   :|....:||  |..|:|.:|.:.||||:....|
plant   309 SAITVEWALAELINHPEIMKKAQQEIEQV---VGNKRVVEESDLCNLSYTQAVVKETMRLHPGGP 370

  Fly   434 LGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPF 498
            :.:....:|..|.| :.|...:.::.:.|||..|...:.:|.|||||||..::....: .:.:.|
plant   371 IFVRESDEECAVAG-FRIPAKTRVIVNVWAIGRDSNQWEDPLEFRPERFEGSEWKVMS-EKMMSF 433

  Fly   499 SSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDM-AGESGITLTP 548
            .:|.|.||||:|....:.:....|::.|.|::....::|. .|.|....||
plant   434 GAGRRSCPGEKMVFRFVPIILAAIIQCFELKVKGSVDMDEGTGSSLPRATP 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	121/536 (23%)
CYP93D1	NP_196307.1	p450	7..500	CDD:299894	124/565 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050