DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phm and CYP91A2

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_195459.1	Gene:	CYP91A2 / 829897	AraportID:	AT4G37430	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	139/570 - (24%)
Similarity:	245/570 - (42%)	Gaps:	139/570 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LSILLVPGALVLVI----LYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAP-HKSLQKLAKR 79
            |..:|:| .|.|||    ||...::.|     .||||...||:|:|..:  :.| |:.||:.:.:
plant     2 LYFILLP-LLFLVISYKFLYSKTQRFN-----LPPGPPSRPFVGHLHLM--KPPIHRLLQRYSNQ 58

  Fly    80 YGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLT-------HGIMG---------G 126
            ||.||.|:.|....||::..:|.::.|  :.|::....||.||       |..:|         .
plant    59 YGPIFSLRFGSRRVVVITSPSLAQESFTGQNDIVLSSRPLQLTAKYVAYNHTTVGTAPYGDHWRN 123

  Fly   127 FGIICAQEDI-------WRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAK 184
            ...||:||.:       ::|.|::.|                .|:..|::|             .
plant   124 LRRICSQEILSSHRLINFQHIRKDEI----------------LRMLTRLSR-------------Y 159

  Fly   185 KSCASEVNPLPALHHSLGNIINDLVFG-----ITYKRDDPDWLYLQRLQEEGVKLI-------GV 237
            ...::|.|..  .|..|..:::||.|.     :|.||...|.:..:...|...||:       |.
plant   160 TQTSNESNDF--THIELEPLLSDLTFNNIVRMVTGKRYYGDDVNNKEEAELFKKLVYDIAMYSGA 222

  Fly   238 SGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQL 302
            :...::||.|:           |...|      :::.|:|.|:.:.:            .|||.|
plant   223 NHSADYLPILK-----------LFGNK------FEKEVKAIGKSMDD------------ILQRLL 258

  Fly   303 EKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADL 367
              ::.|:.||.:                        .::.|.::::....:.|.|..::.|:..:
plant   259 --DECRRDKEGN------------------------TMVNHLISLQQQQPEYYTDVIIKGLMMSM 297

  Fly   368 FGAGVDTSLATLRWFLLYLARE-QRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIR 429
            ..||.:||..||.|.:..|.|. :..::...|:...:|....::|  :..|.||:..:|||.|:.
plant   298 MLAGTETSAVTLEWAMANLLRNPEVLEKARSEIDEKIGKDRLIDESDIAVLPYLQNVVSETFRLF 362

  Fly   430 SVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQ 494
            .|.|..||....::..:|.|.:...::::.:.||||.||..:.|||:|.|:|:....|:.....:
plant   363 PVAPFLIPRSPTDDMKIGGYDVPRDTIVMVNAWAIHRDPEIWEEPEKFNPDRYNDGCGSDYYVYK 427

  Fly   495 FIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDMAGESGI 544
            .:||.:|.|.|||..:.:.|:||..|.:::.|..|...|.|:||:..:|:
plant   428 LMPFGNGRRTCPGAGLGQRIVTLALGSLIQCFEWENVKGEEMDMSESTGL 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	129/537 (24%)
CYP91A2	NP_195459.1	CYP81	60..485	CDD:410746	116/504 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.050