DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP81F4

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_195457.1	Gene:	CYP81F4 / 829895	AraportID:	AT4G37410	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	575	Identity:	142/575 - (24%)
Similarity:	243/575 - (42%)	Gaps:	118/575 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ILLVPGALVLV---ILYLCERQCNDLMGAPPPGP-WGLPFLGYLPFLDARAP-HKSLQKLAKRYG 81
            ::::|.||.|:   ..:..::|...|    ||.| :.||.||:  .|..:.| |:...:|:..:|
plant     5 VIILPLALFLLAYKFFFTSKKQRYYL----PPSPSYSLPILGH--HLLIKPPVHRLFHRLSNIHG 63

  Fly    82 GIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHG-IMGGFGIICAQE--DIWRHAR 141
            .||.|::|....||:|.::|.|:.|  :.||:....|.:||.. |...:..|....  |.||:.|
plant    64 PIFYLRLGSRRAVVISSSSLARECFTGQNDVIVSNRPRFLTSKYIAYNYTTIATTSYGDHWRNLR 128

  Fly   142 RETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSL--GNI 204
            |  |..|:.:...|....|..|.|        |..|:....::.:...:...|.::.:.|  .||
plant   129 R--ICSLEIVSSKRLANFLHIRKE--------EIQRMLTRLSRDARVGKEVELESILYDLTFNNI 183

  Fly   205 INDLVFGITYKRDDPDWLYLQRLQEEGVKLI-----------GVSGVVNFLPWLRHLPANVRNIR 258
            :. :|.|..|..||..       .:|..:|.           |......:||:::
plant   184 VR-MVTGKIYYGDDVS-------DKEEAELFKKLFTFITTNSGARHPGEYLPFMK---------- 230

  Fly   259 FLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEAD 323
                       |:....|   :.:|...||..|:     |||.|
plant   231 -----------IFGGSFE---KEVKAAAKVIDEM-----LQRLL--------------------- 255

  Fly   324 EDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAR 388
             |:.:||::.    ..::.|.|:::..|.:.|.|..::.|:..:..|..:||..|:.|.:..|..
plant   256 -DECKSDKDG----NTMVNHLLSLQQDDPEYYTDIIIKGLMLGIMVASSETSALTIEWAMASLLN 315

  Fly   389 E----QRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVG 447
            .    .:.:..:.|:   :|....:||  :..|.||:..:|||:|:....|:.:|....|:..:|
plant   316 HPKVLDKVKLEIDEI---IGQDRLIEESDIANLPYLQNVVSETLRLHPAAPVLVPRSTAEDIKIG 377

  Fly   448 DYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMAR 512
            .|.:...:|::.:.||||.||..:.|||.|.||||...:|........|.|.||.|:|||..:|.
plant   378 GYDVPRDTMVMVNAWAIHRDPDLWTEPERFNPERFNGGEGEKDDVRMLIAFGSGRRICPGVGLAH 442

  Fly   513 MILTLFTGRILRRFHLELPSGTEVDMAGESGIT---LTPTPHMLR----FTKLPA 560
            .|:||..|.:::.|..:..:..|:||:...|:.   :.|...:.:    ..||||
plant   443 KIVTLALGSLIQCFDWKKVNEKEIDMSEGPGMAMRMMVPLRALCKTRPIMNKLPA 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	132/538 (25%)
CYP81F4	NP_195457.1	CYP81	63..482	CDD:410746	120/494 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050