DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phm and CYP81D4

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_195450.1	Gene:	CYP81D4 / 829888	AraportID:	AT4G37330	Length:	492	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	130/537 - (24%)
Similarity:	224/537 - (41%)	Gaps:	100/537 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAP-HKSLQKLAKRYGG--IFELKMGR 90
            |.:.:|...:|:.|    .||.....||.:|:|..|  :.| |::...|:|..|.  :|.|::|.
plant    17 LAIFLLTRSKRKLN----LPPSPAISLPVIGHLHLL--KPPLHRTFLSLSKSIGNAPVFHLRLGN 75

  Fly    91 VPTVVLSDAALVRD-FFRRDVMTGRAPLY---------LTHGIMGGFGIICAQEDIWRHARRETI 145
            ....|:|..::..: |.:.||:....|.:         .|:.:...:|      |.||:.||  |
plant    76 RLVYVISSRSIAEECFTKNDVVLANRPKFTISKHLGYNATYLLSASYG------DHWRNLRR--I 132

  Fly   146 DWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCAS--EVNPLPALHHSLGNIINDL 208
            ..::.....|....|..|        .||..||....::.|...  ||.....|.:...|....:
plant   133 AAVEIFSTHRLNSFLYIR--------KDEIRRLISHLSRDSLHGFVEVEMKTLLTNLASNTTIRM 189

  Fly   209 VFGITY-KRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYD 272
            :.|..| ..|:.|...::.|..|.|...|....:::|..||.:.:                  |:
plant   190 LAGKRYFGEDNDDAKLVKNLVSEAVTSAGAGNPIDYLSILRWVSS------------------YE 236

  Fly   273 RIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEP 337
            :.::..|.|.   ....::|.::||.:::                                  :.
plant   237 KRIKNLGNRF---DTFLQKLVDEKRAEKE----------------------------------KG 264

  Fly   338 ECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH-ELLL 401
            |.:::|.||::|.....|.|..::.::..|..||.|||..||.|.:..|.......::.. |:..
plant   265 ETMIDHLLALQDIQPDYYTDVIIKGIILTLIIAGTDTSSVTLEWAMSNLLNHPEILKKARMEIDE 329

  Fly   402 PLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAI 464
            .:|....::|  :..|:||::.:.||:|:...|||.:||...|:..||.|.|..|:|::.:.||:
plant   330 KVGLDRLVDESDIVNLSYLQSIVLETLRMYPAVPLLLPHLSSEDCKVGGYDIPSGTMVLTNAWAM 394

  Fly   465 HMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLE 529
            |.||..:.:||.|:|||| ..:|..:   :.|.|..|.|.|||..:|..::....|.:::.|..|
plant   395 HRDPEVWEDPEIFKPERF-EKEGEAE---KLISFGMGRRACPGAGLAHRLINQALGSLVQCFEWE 455

  Fly   530 LPSGTEVDMAGESGITL 546
            ......|||..:.|.||
plant   456 RVGEDFVDMTEDKGATL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	125/517 (24%)
CYP81D4	NP_195450.1	p450	1..485	CDD:386267	130/537 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050