DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and FAH1

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_195345.1	Gene:	FAH1 / 829779	AraportID:	AT4G36220	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	585	Identity:	140/585 - (23%)
Similarity:	237/585 - (40%)	Gaps:	131/585 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLVPGALVLVILYLCERQCNDLMGAP--PPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFE 85
            |::..:|.:.|.::..|:      .|  ||||.|.|.:|.:..:| :..|:.|..|||:|||:..
plant    19 LVIVVSLFIFISFITRRR------RPPYPPGPRGWPIIGNMLMMD-QLTHRGLANLAKKYGGLCH 76

  Fly    86 LKMGRVPTVVLSDAALVRDFFR-RDVMTGRAPL-----YLTHG----IMGGFGIICAQEDIWRHA 140
            |:||.:....:|...:.|...: :|.:....|.     |||:.    ....:|      ..||..
plant    77 LRMGFLHMYAVSSPEVARQVLQVQDSVFSNRPATIAISYLTYDRADMAFAHYG------PFWRQM 135

  Fly   141 RRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSC--ASEVNPLPALHHSLGN 203
            |:..:  :|.....|.......|.|      ||:.||      ..||  ...:|....:.....|
plant   136 RKVCV--MKVFSRKRAESWASVRDE------VDKMVR------SVSCNVGKPINVGEQIFALTRN 186

  Fly   204 IINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLP---WLRHLPANVRNIRFLLEGKA 265
            |.....||...::...:::   |:.:|..||.|...|.:|:|   |:.....|.|    |::.:.
plant   187 ITYRAAFGSACEKGQDEFI---RILQEFSKLFGAFNVADFIPYFGWIDPQGINKR----LVKARN 244

  Fly   266 KTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESD 330
            ......|.|::   :.:|:|                                |...|.:|.:..|
plant   245 DLDGFIDDIID---EHMKKK--------------------------------ENQNAVDDGDVVD 274

  Fly   331 EEDTYEPECILEHFLAVRDTDSQLYCD------------DQLRHLLADLFGAGVDTSLATLRWFL 383
            .:       :::..||....:::|..:            |.::.::.|:...|.:|..:.:.|.|
plant   275 TD-------MVDDLLAFYSEEAKLVSETADLQNSIKLTRDNIKAIIMDVMFGGTETVASAIEWAL 332

  Fly   384 LYLARE----QRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKE 442
            ..|.|.    :|.|:.|.|:   :|....:||  :|.|.||:..:.||:|:...:|| :.|...|
plant   333 TELLRSPEDLKRVQQELAEV---VGLDRRVEESDIEKLTYLKCTLKETLRMHPPIPL-LLHETAE 393

  Fly   443 NFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP------QFIPFSSG 501
            :..:..:||...|.::.:.:||..||.::.:|:.|||.|||...    .|.      :||||.||
plant   394 DTSIDGFFIPKKSRVMINAFAIGRDPTSWTDPDTFRPSRFLEPG----VPDFKGSNFEFIPFGSG 454

  Fly   502 YRMCPGEEMARMILTLFTGRILRRFHLELPSG---TEVDMAGESGITLTPTPHMLRFTKLPAVEM 563
            .|.|||.::....|.|....||..|..:||.|   :|:||....|:|   .|...|...:|...:
plant   455 RRSCPGMQLGLYALDLAVAHILHCFTWKLPDGMKPSELDMNDVFGLT---APKATRLFAVPTTRL 516

Fly 564 563
plant 517 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	133/547 (24%)
FAH1	NP_195345.1	PLN02183	1..520	CDD:165828	140/585 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000