DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP82C2

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_194925.1	Gene:	CYP82C2 / 829327	AraportID:	AT4G31970	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	140/570 - (24%)
Similarity:	235/570 - (41%)	Gaps:	105/570 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SLSILLVPGALVLVILYLC----ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAP--HKSLQKLA 77
            ||..|.||   :||.:::.    .::...:....|.|.|  |.:|:|..|..:..  :::|.|:|
plant     4 SLFSLFVP---ILVFVFIALFKKSKKPKHVKAPAPSGAW--PIIGHLHLLSGKEQLLYRTLGKMA 63

  Fly    78 KRYGGIFELKMGRVPTVVLSDAALVRDFFR-RDVMTGRAPLYLTHGIMG------GFGIICAQED 135
            .:||....|::|...|.|:|...:.:|.|. .|......|:......||      ||....|
plant    64 DQYGPAMSLRLGSSETFVVSSFEVAKDCFTVNDKALASRPITAAAKHMGYDCAVFGFAPYSA--- 125

  Fly   136 IWRHARR-ETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHH 199
            .||..|: .|::.|.    .||...|:......|:..:.:   |:....||..:..|  :..|..
plant   126 FWREMRKIATLELLS----NRRLQMLKHVRVSEISMVMQD---LYSLWVKKGGSEPV--MVDLKS 181

  Fly   200 SLGNI-INDLVFGITYKRD------DPDWLYLQRLQEEGV----KLIGVSGVVNFLP---WLRHL 250
            .|.:: :|.:|..:..||.      .|:.....|...:||    .|:|:..|.:..|   |
plant   182 WLEDMSLNMMVRMVAGKRYFGGGSLSPEDAEEARQCRKGVANFFHLVGIFTVSDAFPKLGW---- 242

  Fly   251 PANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADP 315
                    |..:|       :::.::..|   :|...:.:...|..|.||::...:...|...|.
plant   243 --------FDFQG-------HEKEMKQTG---RELDVILERWIENHRQQRKVSGTKHNDSDFVDV 289

  Fly   316 SQEQSEADEDDEESDEEDTYEPECILEH--FLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLAT 378
            ....:|..:...             |:|  ..:::.|     |       ||.:.| |.:||.:|
plant   290 MLSLAEQGKFSH-------------LQHDAITSIKST-----C-------LALILG-GSETSPST 328

  Fly   379 LRWFL-LYLAREQRCQRRLHELLLPLGPSPTLE--ELEPLAYLRACISETMRIRSVVPLGIPHGC 440
            |.|.: |.|..:...::...|:.:.:|....:|  ::|.|.|::|.|.||:|:....||......
plant   329 LTWAISLLLNNKDMLKKAQDEIDIHVGRDRNVEDSDIENLVYIQAIIKETLRLYPAGPLLGHREA 393

  Fly   441 KENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADG-AYQAPPQ---FIPFSSG 501
            .|:..|..|.::.|:.::.:.|.|..||..:.||.|||||||:|.:. .:....|   .:||.||
plant   394 IEDCTVAGYNVRRGTRMLVNVWKIQRDPRVYMEPNEFRPERFITGEAKEFDVRGQNFELMPFGSG 458

  Fly   502 YRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDMAGESGITL---TP 548
            .|.|||..:|..:|.|...|.|:.|.::......|||....|:|:   ||
plant   459 RRSCPGSSLAMQVLHLGLARFLQSFDVKTVMDMPVDMTESPGLTIPKATP 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	133/536 (25%)
CYP82C2	NP_194925.1	CYP82	67..516	CDD:410747	122/502 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050