DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP71A19

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_193065.1	Gene:	CYP71A19 / 826959	AraportID:	AT4G13290	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	146/566 - (25%)
Similarity:	238/566 - (42%)	Gaps:	115/566 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            |:.||   ||:|:...|.....|:|  ..||.||.||.:|.|..|.... |:||:.|:.|||.:.
plant    10 LTTLL---ALLLLKSILKRTTTNNL--NLPPSPWRLPVIGNLHQLSLNT-HRSLRSLSLRYGPLM 68

  Fly    85 ELKMGRVPTVVLSDAALVRDFFRR-DVMTGRAP--LYLTHGIMGGFGIICA-QEDIWRHARRETI 145
            .|..||.|.:::|.|.:..|..:. ||:....|  ..:...:.||..:..| ..:.|:..:...|
plant    69 LLHFGRTPVLIVSSADVAHDILKTYDVICANRPKTKVIDKILRGGRDVAFAPYGEYWKQMKSICI 133

  Fly   146 DWLKALGMTR-----RPGELRARLERRIARGVDECVRLFDTEAKKSCA--SEVNPLPALHHSLGN 203
            ..|.:..|.|     |..|::..:|:              .|...||:  |.|| |..|..:|.|
plant   134 QNLLSNKMVRSYKKIREDEIKLMIEK--------------VENASSCSPPSPVN-LSQLFMTLTN 183

  Fly   204 -IINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGV----SGVVNFLPWLRHLPANVRNIRFLLEG 263
             ||.....|..|..           :|:|:.:..:    |.:|...|...::|    ::.::.:.
plant   184 DIICRAALGRKYSS-----------KEDGIDVENIVRAFSALVGEFPIGEYIP----SLSWIDKI 233

  Fly   264 KAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEE 328
            :.:.|            :::|..|.|.|..|             |..||.:.:.:       |..
plant   234 RGQDH------------KMEEVDKRFDEFLE-------------RVVKEHEDANK-------DTR 266

  Fly   329 SDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQ 393
            ||..||         .|.::...|      .|:.::.|:|.||..|||:.|.|.:..|.|..:..
plant   267 SDLVDT---------LLTIQSDKS------ALKLIIWDMFLAGTATSLSFLEWAMTELMRNPKVM 316

  Fly   394 RRLHELLLP---LGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGS 455
            ::|.|.:..   .|...|.:|.|.:.||:|.|.|.:|:|...||.:|....|:..:..|.|..|:
plant   317 KKLQEEIRSSSRQGLFVTEKEAEKMDYLQAVIKEALRLRPPAPLMVPRVFSEDVTLKGYNIPAGT 381

  Fly   456 MIVCSEWAIHMDPVAFP-EPEEFRPERFLTADGAYQAPP-QFIPFSSGYRMCPGEEMARMILTLF 518
            .::.:.|||..|...:. :.|||||||.|.:...:|... :||||.||.|:|||......::.:.
plant   382 QVIINAWAIQRDTTTWGIDAEEFRPERHLDSILDFQGQDFKFIPFGSGKRICPGIGFTSALIGVT 446

  Fly   519 TGRILRRFHLEL---PSGTEVDMAGESGITLTPTPHMLRFTKLPAV 561
            ...|::||:..:   |...:.|:...:|:.:        |.|.|.:
plant   447 LANIVKRFNWRMDVEPQRVQHDLTEATGLVV--------FRKFPLI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	134/529 (25%)
CYP71A19	NP_193065.1	p450	25..487	CDD:386267	139/548 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050