DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP706A4

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_192967.1	Gene:	CYP706A4 / 826839	AraportID:	AT4G12300	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	161/577 - (27%)
Similarity:	253/577 - (43%)	Gaps:	118/577 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SILLVPGALVL------VILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKR 79
            :|.|.|.|:|:      ::.|:.:|.....:   ||||.|||.:|.|||||... |.....||:.
plant    12 TINLTPYAIVILTTVFSILWYIFKRSPQPSL---PPGPRGLPIVGNLPFLDPDL-HTYFANLAQS 72

  Fly    80 YGGIFELKMGRVPTVVLSDAALVRD--------FFRRDV-MTGRAPLYLTHGIMGGFGIICAQED 135
            :|.||:|.:|...|:|::..:|.|:        |..||| :||||..|      ||..|:.....
plant    73 HGPIFKLNLGSKLTIVVNSPSLAREILKDQDINFSNRDVPLTGRAATY------GGIDIVWTPYG 131

  Fly   136 I-WRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHH 199
            . ||..|:..:  ||.|  :|:..:....|.|:..|   |..|....:.:|.  |.|.....|..
plant   132 AEWRQLRKICV--LKLL--SRKTLDSFYELRRKEVR---ERTRYLYEQGRKQ--SPVKVGDQLFL 187

  Fly   200 SLGNIINDLVFGITYKRDDPDWL--YLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLE 262
            ::.|:..::::|.:.|.::.:.:  ..:.:..|..:|:....|.:|.|||         .||.|:
plant   188 TMMNLTMNMLWGGSVKAEEMESVGTEFKGVISEITRLLSEPNVSDFFPWL---------ARFDLQ 243

  Fly   263 GKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDE 327
            |..|...:..|.::|...|..|:.|..:                               ..:|||
plant   244 GLVKRMGVCARELDAVLDRAIEQMKPLR-------------------------------GRDDDE 277

  Fly   328 ESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRH---LLADLFGAGVDTSLATLRWFLLYLARE 389
            ..|         .|::.:.::|.:........:.|   ||.|:...|.|||..|:.:.:..|...
plant   278 VKD---------FLQYLMKLKDQEGDSEVPITINHVKALLTDMVVGGTDTSTNTIEFAMAELMSN 333

  Fly   390 ----QRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGD 448
                :|.|..|.|:   :|....:||  :..|.|:.|.:.||:|:...:||.:||...||.|||.
plant   334 PELIKRAQEELDEV---VGKDNIVEESHITRLPYILAIMKETLRLHPTLPLLVPHRPAENTVVGG 395

  Fly   449 YFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTAD-----GAYQAPPQFIPFSSGYRMCPGE 508
            |.|...:.|..:.|:|..||..:..|.||||||||..:     ||..:   :.||.||.|:|.|.
plant   396 YTIPKDTKIFVNVWSIQRDPNVWENPTEFRPERFLDNNSCDFTGANYS---YFPFGSGRRICAGV 457

  Fly   509 EMA-RMIL-TLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHMLRFTKLPAVEM 563
            .:| ||:| ||.|  :|..|..::|.|..:|:..:.||.|.        .|:|.|.:
plant   458 ALAERMVLYTLAT--LLHSFDWKIPEGHVLDLKEKFGIVLK--------LKIPLVAL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	151/533 (28%)
CYP706A4	NP_192967.1	p450	17..512	CDD:386267	159/572 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3251
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050