DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phm and CYP71A22

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_680110.1	Gene:	CYP71A22 / 823989	AraportID:	AT3G48310	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	131/547 - (23%)
Similarity:	230/547 - (42%)	Gaps:	95/547 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            :.|:|:...:.:.||:.. :|........|..|..||.:|.|..| .|.||:||..|:.|||.:.
plant     5 IRIILLSLIIFITILFFI-KQKKGKKSNTPASPPRLPLIGNLHQL-GRHPHRSLCSLSNRYGPLM 67

  Fly    85 ELKMGRVPTVVLSDAALVRDFFRR-DVMTGRAP--------LYLTHGI-MGGFGIICAQEDIWRH 139
            .|:.|.||.:|:|.|.:.||..:. |.:....|        .|....: :..:|      :.||.
plant    68 LLRFGLVPVLVVSSADVARDILKTYDRVFASRPRSKIFEKIFYEARDVALAPYG------EYWRQ 126

  Fly   140 ARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNI 204
            .:...:..|....|.|....:|           .|.:.|...:.:||.:.:||    |...||::
plant   127 MKSVCVLHLLTNKMVRSFRNVR-----------QEEISLMMEKIQKSSSLQVN----LSELLGSL 176

  Fly   205 INDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHA 269
            .||::..:...|...|....:.|.:...||:|...|..::|||                     |
plant   177 TNDVISRVALGRKYSDETDFKELMKRLTKLLGEFCVGTYVPWL---------------------A 220

  Fly   270 IYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDT 334
            ..|.|                     ..|..||:|    ...:.|...|:...|.:|.::...|
plant   221 WIDWI---------------------SGLDGQLKK----TGNDLDEFLEKVVQDHEDGDAQRTD- 259

  Fly   335 YEPECILEHFLAVRDTDSQLYCDDQL--RHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH 397
                 .::..|.::...|..:..|:|  :.::.|:...|.|||.|.:.|.:..|.....|..||.
plant   260 -----FVDVLLRIQREKSVGFEIDRLSIKAIILDVVVGGTDTSYALMEWAMTELLHRPECLNRLQ 319

  Fly   398 ELLLPL---GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVC 459
            |.:..:   ..|.:.::::.:.||:|.|.||||:...:||.:||...::..:|||.|..|:.::.
plant   320 EEVRTICKGNSSVSEDDIKDMNYLKAVIKETMRLHPPLPLMVPHESTQDVRLGDYHIPAGTQVMI 384

  Fly   460 SEWAIHMDPVAF-PEPEEFRPERFLTADGAYQAPP-QFIPFSSGYRMCPGEEMARMILTLFTGRI 522
            :.|||..:...: |:.|:|||||.|.:...::... :.|||.:|.|:||....|.:::.:....:
plant   385 NAWAIGREAATWGPDAEKFRPERHLNSSVDFRGHNFELIPFGAGRRICPAISFAVILIEVTLANL 449

  Fly   523 LRRFHLELPS---GTEVDMAGESGITL 546
            :.|:...||.   ..:.::|..:|:.:
plant   450 VHRYDWRLPEEYIEDQTNVAESTGMVI 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	126/518 (24%)
CYP71A22	NP_680110.1	p450	24..482	CDD:299894	127/527 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050