DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP71B36

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_189263.1	Gene:	CYP71B36 / 822236	AraportID:	AT3G26320	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	134/566 - (23%)
Similarity:	230/566 - (40%)	Gaps:	119/566 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAK 78
            |.::..||:|.:...|:....:...:|..    ..||.|.|.|.:|.|..| ...||:||.:|:|
plant     1 MATILFLSLLFLSCILLAAFTHKKRQQHQ----RKPPSPPGFPIIGNLHQL-GELPHQSLWRLSK 60

  Fly    79 RYGGIFELKMGRVPTVVLSDAALVRDFFR--------RDVMTGRAPLYLTHGIMG-GFGIICAQE 134
            :||.:..||.|.:||||:|.:...:...:        |..:.|  |..|::..:. .|...   :
plant    61 KYGHVMLLKFGSIPTVVVSSSETAKQVLKIHDLHCCSRPSLAG--PRALSYNYLDIAFSPF---D 120

  Fly   135 DIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHH 199
            |.|:..||..:   :.|...:|....:...|       ||..:|.|:.::.  ||:..|:
plant   121 DYWKELRRICV---QELFSVKRVQSFQPIKE-------DEVKKLIDSVSES--ASQGTPV----- 168

  Fly   200 SLGNIINDL--------VFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLP-------WLRH 249
            :|......|        .||:.::....:....::|..:....:|.....::.|       ||..
plant   169 NLSEKFTSLTVRVTCKATFGVNFQGTVLNSDRFEKLIHDTYLFLGSFSASDYFPNGGWIIDWLTG 233

  Fly   250 LPA-NVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEA 313
            |.. ..|::|.|       .|.|:::.:...|..||..:.|.:|     |.| ||||
plant   234 LHGQRERSVRAL-------DAFYEQMFDLHKQGNKEGVEDFVDL-----LLR-LEKE-------- 277

  Fly   314 DPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLAT 378
                                    |.::.:....|         :.::.:|.::...|:.||..|
plant   278 ------------------------ETVIGYGKLTR---------NHIKAILMNVLIGGIGTSAIT 309

  Fly   379 LRWFLLYLAREQRCQRRLH-ELLLPLGPSP--TLEELEPLAYLRACISETMRIRSVVPLGIPHGC 440
            :.|.:..|.|..|..:::. |:...:|...  ||::::.|.||:..|:||.|:....|..||...
plant   310 MTWAMTELMRNPRVMKKVQSEIRNQIGKKSMITLDDIDQLHYLKMVINETWRLHPPSPFLIPRQV 374

  Fly   441 KENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERF----LTADGAYQAPPQFIPFSSG 501
            ...|.:.||.|...:.:..:.|||..||..:.:||||.||||    :.|.|.:.   :.:||.||
plant   375 MSEFELNDYVIPVKTRLYVNVWAIGRDPDTWKDPEEFLPERFVNSSIDAKGQHF---ELLPFGSG 436

  Fly   502 YRMCPGEEMARMILTLFTGRILRRFHLELPSG---TEVDMAGESGI 544
            .||||...|...::......:|..|..::|.|   .::|:....|:
plant   437 RRMCPAMYMGTTMVEFGLANMLYHFDWKIPVGMVAEDIDLEESPGL 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	128/531 (24%)
CYP71B36	NP_189263.1	p450	20..498	CDD:299894	129/547 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050