DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP71B23

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_189252.1	Gene:	CYP71B23 / 822222	AraportID:	AT3G26210	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	142/577 - (24%)
Similarity:	230/577 - (39%)	Gaps:	130/577 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            |..||:...|::.|::..:.|.:.|  ..||||..||.:|.|.:|:. .|||.|..|.|.:|.:.
plant     5 LCFLLLLLLLLVTIIFTRKSQSSKL--KLPPGPPKLPIIGNLHYLNG-LPHKCLLNLWKIHGPVM 66

  Fly    85 ELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDW-L 148
            :|::|.||.||:|......:..:            ||.:     ..|::.:.   ...:||.: .
plant    67 QLQLGYVPLVVISSNQAAEEVLK------------THDL-----DCCSRPET---IASKTISYNF 111

  Fly   149 KALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGIT 213
            |.:|......|.||.  |::|     .:.||..:...|                         ..
plant   112 KDIGFAPYGEEWRAL--RKLA-----VIELFSLKKFNS-------------------------FR 144

  Fly   214 YKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEAC 278
            |.|::.:.|.:::|.|...|               ..|.|::...|.|..     :|..|:  |.
plant   145 YIREEENDLLVKKLSEASEK---------------QSPVNLKKALFTLSA-----SIVCRL--AF 187

  Fly   279 GQRLKEKQKVFKELQEQKRLQRQLEKEQLR------------------QSKEADPSQEQSEAD-- 323
            ||.|.|.:.:.::..|.  |..:.||.|.:                  |||    |..:..||
plant   188 GQNLHESEFIDEDSMED--LASRSEKIQAKFAFSNFFPGGWILDKITGQSK----SLNEIFADLD 246

  Fly   324 ------EDDEESDEEDTYEPECILEHFLAVRDTDSQ----LYCDDQLRHLLADLFGAGVDTSLAT 378
                  .||.........|...:::..:.:.:..||    ....|.::.:::|:|.|||:||..|
plant   247 GFFNQVLDDHLKPGRKVLETPDVVDVMIDMMNKQSQDGSFKLTTDHIKGIISDIFLAGVNTSATT 311

  Fly   379 LRWFLLYLAREQRCQRRLH-ELLLPLGPSP---TLEELEPLAYLRACISETMRIRSVVPLGIPHG 439
            :.|.:..|.|..|..:::. |:...||...   |.::|..|.|.:..|.||.|:....||.:|..
plant   312 ILWAMTELIRNPRVMKKVQDEVRTVLGEKRDRITEQDLNQLNYFKLVIKETFRLHPAAPLLLPRE 376

  Fly   440 CKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP-QFIPFSSGYR 503
            ......:..|.|...:.|:.:.:||..||..:..||||:||||:.:...|:... :.:||.||.|
plant   377 AMAKIKIQGYDIPEKTQIMVNVYAIGRDPDLWENPEEFKPERFVDSSVDYRGLNFELLPFGSGRR 441

  Fly   504 MCPGEEMARMILTLFTGRILRRFHLELPSG---TEVDMAGESGI--------TLTPT 549
            :|||..|....:.|....:|..|...||.|   .::|:..|..|        .|.||
plant   442 ICPGMTMGIATVELGLLNLLYFFDWGLPEGRTVKDIDLEEEGAIIIGKKVSLELVPT 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	135/548 (25%)
CYP71B23	NP_189252.1	CYP71-like	62..493	CDD:410695	117/510 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.050