DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP82G1

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_189154.1	Gene:	CYP82G1 / 822110	AraportID:	AT3G25180	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	596	Identity:	143/596 - (23%)
Similarity:	229/596 - (38%)	Gaps:	142/596 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SVQSLSILLVPGALVLVI---------LYLCERQCNDLMGAPPPGPWG-LPFLGYLPFL-DARAP 69
            |...||:.    :|.|||         |..||...:.:     |.|.| ||..|:|..| ..:..
plant     6 STLQLSLF----SLALVIFGYIFLRKQLSRCEVDSSTI-----PEPLGALPLFGHLHLLRGKKLL 61

  Fly    70 HKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRD-FFRRDVMTGRAPLYLTHGIMGGFG----I 129
            .|.|..:::::|.||.||:|....||.||...|:| |...|:.|...| .:..|...|:.    .
plant    62 CKKLAAMSQKHGPIFSLKLGFYRLVVASDPKTVKDCFTTNDLATATRP-NIAFGRYVGYNNASLT 125

  Fly   130 ICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPL 194
            :....|.||..|:.....|.:.......|.:|                          :||||.|
plant   126 LAPYGDYWRELRKIVTVHLFSNHSIEMLGHIR--------------------------SSEVNTL 164

  Fly   195 PALHHSLGN----------IINDLVFGITYKR-----------DDPDWLYLQRLQE-EGVKLIGV 237
             ..|...||          :...|.|.|..::           :..:|.|.:.|:. |.:.:|.:
plant   165 -IKHLYKGNGGTSIVKIDMLFEFLTFNIILRKMVGKRIGFGEVNSDEWRYKEALKHCEYLAVIPM 228

  Fly   238 SGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQ--EQKRLQR 300
            .|.|  :|||..|..            ||.               .:.:::||||.  ..|.|..
plant   229 IGDV--IPWLGWLDF------------AKN---------------SQMKRLFKELDSVNTKWLHE 264

  Fly   301 QLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLA 365
            .|:|                   ....|.|:|.|     |::..|.:...|  :.....:|.::.
plant   265 HLKK-------------------RSRNEKDQERT-----IMDLLLDILPED--IVISGHVRDVIV 303

  Fly   366 D-----LFGAGVDTSLATLRWFL-LYLAREQRCQRRLHELLLPLGPSPTLEE--LEPLAYLRACI 422
            .     |...|.|::..||.|.: |.|......:....|:...:|....:||  ::.|.||:|.:
plant   304 KATILALTLTGSDSTSITLTWAVSLLLNNPAALEAAQEEIDNSVGKGRWIEESDIQNLKYLQAIV 368

  Fly   423 SETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADG 487
            .||.|:....||......:|:..||.|.::.|:.::.:.|.:|.||..:|:|:.|:||||:....
plant   369 KETHRLYPPAPLTGIREAREDCFVGGYRVEKGTRLLVNIWKLHRDPKIWPDPKTFKPERFMEDKS 433

  Fly   488 AYQAPP-QFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPH 551
            ..:... ::|||.||.|.|||..:...::.....|:|:.|.|...|...:|||...|:.| |..:
plant   434 QCEKSNFEYIPFGSGRRSCPGVNLGLRVVHFVLARLLQGFELHKVSDEPLDMAEGPGLAL-PKIN 497

  Fly   552 MLRFTKLPAVE 562
            .:....:|.::
plant   498 PVEVVVMPRLD 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	132/545 (24%)
CYP82G1	NP_189154.1	p450	8..514	CDD:299894	142/594 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050